Results 111 to 120 of about 1,395,428 (175)

Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice.

PLoS ONE, 2019
Middle East respiratory syndrome-coronavirus (MERS-CoV) is an emerging virus that causes severe disease with fatal outcomes; however, there are currently no approved vaccines or specific treatments against MERS-CoV.
Hirofumi Kato, Mutsuyo Takayama-Ito, Itoe Iizuka-Shiota, Shuetsu Fukushi, Guillermo Posadas-Herrera, Madoka Horiya, Masaaki Satoh, Tomoki Yoshikawa, Souichi Yamada, Shizuko Harada, Hikaru Fujii, Miho Shibamura, Takuya Inagaki, Kinjiro Morimoto, Masayuki Saijo, Chang-Kweng Lim   +15 more
doaj   +1 more source

Monitoring of Biodistribution and Persistence of Conditionally Replicative Adenovirus in a Murine Model of Ovarian Cancer Using Capsid-Incorporated mCherry and Expression of Human Somatostatin Receptor Subtype 2 Gene

Molecular Imaging, 2014
A significant limiting factor to the human clinical application of conditionally replicative adenovirus (CRAd)-based virotherapy is the inability to noninvasively monitor these agents and their potential persistence.
Igor P. Dmitriev, Elena A. Kashentseva, Kenneth H. Kim, Qiana L. Matthews, Stephanie S. Krieger, Jesse J. Parry, Kim N. Nguyen, Walter J. Akers, Samuel Achilefu, Buck E. Rogers, Ronald D. Alvarez, David T. Curiel   +11 more
doaj   +1 more source

Pseudoviruses, a safer toolbox for vaccine development against enveloped viruses

Expert Review of Vaccines
Introduction Pseudoviruses are recombinant, replication-incompetent, viral particles designed to mimic the surface characteristics of native enveloped viruses. They are a safer, and cost-effective research alternative to live viruses.
Syamala R. Thimmiraju, Jason T. Kimata, Jeroen Pollet   +2 more
doaj   +1 more source

Inhibitory effects of kaempferol, quercetin and luteolin on the replication of human parainfluenza virus type 2 in vitro [PDF]

三重大学博士(医学)application/pdfThe eight flavonoids, apigenin, chrysin, hesperidin, kaempferol, myricetin, quercetin, rutin and　luteolin were tested for the inhibition of human parainfluenza virus type 2 (hPIV-2) replication.　Three flavonoids out of the eight,
Sakai-Sugino, Kae, スギノ, カエ, 杉野, 香江   +2 more
core   +1 more source

Establishment of an induced pluripotent cell line from Taiwan black silkie chick embryonic fibroblasts for replication-incompetent virus production. [PDF]

Sci Rep, 2019
Liou JF, Wu WR, Chen LR, Shiue YL.
europepmc   +1 more source

ISGylation and phosphorylation : two protein posttranslational modifications that play important roles in influenza A virus replication [PDF]

, 2008
textTwo posttranslational modifications, ISGylation and phosphorylation, impact the replication of influenza A virus, a human pathogen responsible for high mortality pandemics. The ubiquitin-like ISG15 protein is induced by type 1 interferon (IFN) and is
Hsiang, Tien-ying, 1976-
core  

Multiplex gene editing to target the roots of hepatitis B virus infection. [PDF]

Mol Ther Nucleic Acids
Kumar A, Zoulim F.
europepmc   +1 more source

Structural elucidation of the herpesvirus replication machinery: Cryo-EM insights into helicase-primase complex assembly and mechanisms of antiviral inhibition. [PDF]

Acta Pharm Sin B
Zhou Q, Li B, Shi D, Gao S, Zhan P, Yang J.   +5 more
europepmc   +1 more source

Retroviruses and Cancer: Coevolution and Genetic Exchanges Between the Viral and the Host Genomes. [PDF]

Biology (Basel)
Xia X.
europepmc   +1 more source

It takes two: A two-component system to visualize single-molecule HIV-1 infection <i>in vivo</i>. [PDF]

Mol Ther Adv
Dudek AM.
europepmc   +1 more source