Results 141 to 150 of about 1,158,325 (299)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Circular RNA GATAD2A promotes H1N1 replication through inhibiting autophagy

, 2019
Tianqi Yu, Yingnan Ding, Yina Zhang, Yulan Liu, Yahui Li, Jing Lei, Jiyong Zhou, Suquan Song, Boli Hu   +8 more
openalex   +1 more source

DDX21, a Host Restriction Factor of FMDV IRES-Dependent Translation and Replication [PDF]

, 2021
Sahibzada Waheed Abdullah, Jin’en Wu, Yun Zhang, Manyuan Bai, Junyong Guan, Xiangtao Liu, Shiqi Sun, Huichen Guo   +7 more
openalex   +1 more source

Self-replication [PDF]

Current Biology, 2003
Paul, Natasha, Joyce, Gerald F
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Synthesis of Site-Specific DNA–Protein Conjugates and Their Effects on DNA Replication

, 2014
Jung Eun Yeo, Susith Wickramaratne, Santoshkumar Khatwani, Yen-Chih Wang, Jeffrey S. Vervacke, Mark D. Distefano, Natalia Tretyakova   +6 more
openalex   +1 more source

New Isolates of Pandoraviruses: Contribution to the Study of Replication Cycle Steps [PDF]

, 2018
Ana Cláudia dos Santos Pereira Andrade, Paulo Victor de Miranda Boratto, Rodrigo Araújo Lima Rodrigues, Talita Machado Bastos, Bruna Luiza de Azevedo, Fábio P. Dornas, Danilo Bretas de Oliveira, Betânia Paiva Drumond, Erna Geessien Kroon, Jônatas Santos Abrahão   +9 more
openalex   +1 more source

Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication [PDF]

, 2022
Elizabeth R. Vanderwall, Kaitlyn A. Barrow, Lucille M. Rich, David F. Read, Cole Trapnell, Oghenemega Okoloko, Steven F. Ziegler, Teal S. Hallstrand, Maria P. White, Jason S. Debley   +9 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Structure and interactions of the Bacillus subtilis sporulation inhibitor of DNA replication, SirA, with domain I of DnaA [PDF]

, 2014
Katie H. Jameson, Nadia Rostami, Mark J. Fogg, J.P. Turkenburg, Anne Grahl, Heath Murray, Anthony J. Wilkinson   +6 more
openalex   +1 more source