Results 181 to 190 of about 1,158,325 (299)

HoxA10 Facilitates SHP-1-Catalyzed Dephosphorylation of p38 MAPK/STAT3 To Repress Hepatitis B Virus Replication by a Feedback Regulatory Mechanism [PDF]

, 2019
Qingyu Yang, Zhang Qi, Xuewu Zhang, Lei You, Wenbiao Wang, Weiyong Liu, Yang Han, Chunqiang Ma, Wei Xu, Junbo Chen, Hua Yang, Pin Wan, Yao Zhou, Yingle Liu, Kailang Wu, Ziwen Yang, Jianguo Wu   +16 more
openalex   +1 more source

Regulatory effects of chicken TRIM25 on the replication of ALV-A and the MDA5-mediated type I interferon response [PDF]

, 2020
Jinrun Zhou, Junhong Liu, Hongmei Li, Yue Zhao, Ziqiang Cheng, Yan-meng Hou, Huijun Guo   +6 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Quercetin Regulates Autophagy to Inhibit PRRSV Replication Through the PI3K/Akt/mTOR Signaling Pathway. [PDF]

Viruses
Yang Y, Li X, Shi H, Yu J, Gao C, Liu Y, Feng W, Peng L, Fu B, Yi P.   +9 more
europepmc   +1 more source

Assembly-hub function of ER-localized SNARE proteins in biogenesis of tombusvirus replication compartment

, 2018
Zsuzsanna Sasvári, Nikolay Kovalev, Paulina Alatriste González, Kai Xu, Peter D. Nagy   +4 more
openalex   +2 more sources

The Porcine Deltacoronavirus Replication Organelle Comprises Double-Membrane Vesicles and Zippered Endoplasmic Reticulum with Double-Membrane Spherules [PDF]

, 2019
Nicole Doyle, Philippa C. Hawes, Jennifer Simpson, Lorin Adams, Helena J. Maier   +4 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Torsion is a dynamic regulator of DNA replication stalling and reactivation. [PDF]

Nat Commun
Jia X, Gao X, Zhang S, Inman JT, Hong Y, Singh A, Rashid F, Berger JM, Patel SS, Wang MD.   +9 more
europepmc   +1 more source

Prechemistry versus preorganization in DNA replication fidelity

, 2011
B. Ram Prasad, Arieh Warshel
openalex   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source