Results 231 to 240 of about 1,158,325 (299)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

RETRACTION: Expression of Factor X in BHK-21 Cells Promotes Low Pathogenic Influenza Viruses Replication. [PDF]

Adv Virol
In Virology A.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Chromatin assembly by the histone chaperone HIRA facilitates Human Papillomavirus replication. [PDF]

Tumour Virus Res
Della Fera AN, Chen D, McBride AA.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Post-Translational Modifications in Respiratory Virus Infection: Recent Insights into the Development of In Vitro Models. [PDF]

Int J Mol Sci
Ben Khlifa E, Campese A, Corsi A, Bombieri C, Romanelli MG, Valenti MT, Zipeto D, Castelli M, Lievens PM, Ruggiero A.   +9 more
europepmc   +1 more source

Carbon cycling and phytoplankton responses within highly-replicated shipboard carbonate chemistry manipulation experiments conducted around Northwest European Shelf Seas

, 2014
Sophie Richier, Eric P. Achterberg, Cynthia Dumousseaud, Alex J. Poulton, D. J. Suggett, Toby Tyrrell, Mikhail V. Zubkov, C. Mark Moore   +7 more
openalex   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

How DNA secondary structures drive replication fork instability.

DNA Repair (Amst)
Sethi A, Fernández-Casañas M, Delpino B, Coster G.   +3 more
europepmc   +1 more source

Genetic Optimization of Early 2009 Pandemic H1N1 Vaccine Strains for Improved Replication in Embryonated Chicken Eggs. [PDF]

J Microbiol Biotechnol
Son SE, Song JH, An SH, Lee CY, Kim IH, Kim HW, Choi KS, Kwon HJ.   +7 more
europepmc   +1 more source