Results 1 to 10 of about 2,618,507 (231)

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics [PDF]

open access: goldFrontiers in Genetics, 2016
Genome-wide Association Studies (GWAS) result in millions of summary statistics (``z-scores'') for single nucleotide polymorphism (SNP) associations with phenotypes.
Dominic eHolland   +21 more
doaj   +2 more sources

Do group ensemble statistics bias visual working memory for individual items? A registered replication of Brady and Alvarez (2011) [PDF]

open access: hybridAttention, perception & psychophysics, 2020
We performed a registered and precise replication of Experiment 1 reported in Brady and Alvarez ( Psychological Science , 22 , 384–392, 2011 ). The original experiment found that participants, who were asked to memorize the size of differently colored ...
Frank Papenmeier, J. David Timm
openalex   +2 more sources

A replication of “A quasi-maximum likelihood approach for large, approximate dynamic factor models” (Review of Economics and Statistics, 2012) [PDF]

open access: goldEconomics: Journal Articles, 2020
The authors replicate and extend the Monte Carlo experiment presented in Doz, Giannone and Reichlin (A Quasi-Maximum Likelihood Approach For Large, Approximate Dynamic Factor Models, Review of Economics and Statistics, 2012) on alternative (time-domain ...
Lucchetti Riccardo, Venetis Ioannis A.
doaj   +4 more sources

Inferential statistics as descriptive statistics: there is no replication crisis if we don't expect replication

open access: greenAmerican Statistician, 2018
Statistical inference often fails to replicate. One reason is that many results may be selected for drawing inference because some threshold of a statistic like the P-value was crossed, leading to biased reported effect sizes.
Valentin Amrhein   +2 more
openalex   +2 more sources

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.

open access: yesPLoS Genetics, 2016
Most of the genetic architecture of schizophrenia (SCZ) has not yet been identified. Here, we apply a novel statistical algorithm called Covariate-Modulated Mixture Modeling (CM3), which incorporates auxiliary information (heterozygosity, total linkage ...
Yunpeng Wang   +23 more
doaj   +2 more sources

Statistics in Service of Metascience: Measuring Replication Distance with Reproducibility Rate

open access: goldEntropy
Motivated by the recent putative reproducibility crisis, we discuss the relationship between the replicability of scientific studies, the reproducibility of results obtained in these replications, and the philosophy of statistics. Our approach focuses on
Erkan O. Buzbas, Berna Devezer
doaj   +2 more sources

Publications, replication and statistics in physiology plus two neglected curves

open access: yesJournal of Physiology, 2021
I was asked to write a short editorial to reflect on my links to The Journal of Physiology and to consider some of the changes in physiology reflected in The Journal.
S. Gandevia
semanticscholar   +1 more source

The new normal? Redaction bias in biomedical science

open access: yesRoyal Society Open Science, 2021
A concerning amount of biomedical research is not reproducible. Unreliable results impede empirical progress in medical science, ultimately putting patients at risk.
David Robert Grimes, James Heathers
doaj   +1 more source

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