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Department of Applied Mathematics and Statistics newsletter, January 22, 2024
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Body mass index and type 2 diabetes liability in osteomyelitis and cellulitis: A cross-biobank Mendelian randomization study. [PDF]
Liu F, Luo K, Liu H.
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Immune-Related Mendelian Randomization Signals for Anxiety Disorders Highlight the CD40 Locus on Chromosome 20 (chr20:46118-46130 Mb, GRCh38). [PDF]
Wang L +5 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Improving science will require more than just training. [PDF]
King KM, Lui PP, Dora J.
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Statistical Challenges for Studying Replication
openaire +1 more source
Modelling Between-Cell-Type Heterogeneity in Within-Host Influenza Virus Infection. [PDF]
Yan AWC, Riley S, McCaw JM.
europepmc +1 more source

