Results 221 to 230 of about 2,618,656 (372)
Spiking dynamics of individual neurons reflect changes in the structure and function of neuronal networks. [PDF]
Yang R+4 more
europepmc +1 more source
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen+4 more
wiley +1 more source
A metric of knowledge as information compression reflects reproducibility predictions for biomedical experiments. [PDF]
Fanelli D, Tan PB, Amaral OB, Neves K.
europepmc +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Polygenic Risk Scores in Dilated Cardiomyopathy: Towards the Future. [PDF]
Kramarenko DR+4 more
europepmc +1 more source
Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort [PDF]
Bierut, Laura+3 more
core +1 more source