Results 61 to 70 of about 2,339,539 (318)

Pocket Statistics 2015 [PDF]

open access: yes, 2015
A compact selection of statistics on the social security programmes administered by the Kela. Including both tables and charts, the Pocket statistics presents key data on the benefits provided by the Kela, supplemented by selected data about programmes ...
Kela
core  

Modeling and replicating statistical topology and evidence for CMB nonhomogeneity [PDF]

open access: yesProceedings of the National Academy of Sciences, 2017
Significance Under the general heading of “topological data analysis” (TDA), the recent adoption of topological methods for the analysis of large, complex, and high-dimensional data sets has established that the abstract concepts of algebraic topology provide powerful tools for data analysis.
Robert J. Adler   +2 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Revisiting the Replication Crisis and the Untrustworthiness of Empirical Evidence

open access: yesStats
The current replication crisis relating to the non-replicability and the untrustworthiness of published empirical evidence is often viewed through the lens of the Positive Predictive Value (PPV) in the context of the Medical Diagnostic Screening (MDS ...
Aris Spanos
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

“Cake causes herpes?” - promiscuous dichotomisation induces false positives

open access: yesBMC Medical Research Methodology
Background Continuous biomedical data is often dichotomized into two or more groups for analysis, despite long-standing warnings from statisticians that this constitutes bad practice.
David Robert Grimes, James Heathers
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Pocket Statistics 2011 [PDF]

open access: yes, 2011
A compact selection of statistics on the social security programmes administered by the Kela. Including both tables and charts, the Pocket statistics presents key data on the benefits provided by the Kela, supplemented by selected data about programmes ...
Kela
core  

Statistical reform and the replication crisis

open access: yes, 2018
The replication crisis has prompted many to call for statistical reform within the psychological sciences. Here we examine issues within Frequentist statistics that may have led to the replication crisis, and we examine the alternative---Bayesian statistics---that many have suggested as a replacement.
Colling, Lincoln J, Szucs, Denes
openaire   +2 more sources

RHPMAN: Replication in Highly Partitioned Mobile Ad Hoc Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2014
Accessing data in mobile ad hoc networks is a challenging problem, which is caused by frequent network partitions due to node mobility and due to the impairments of wireless communications.
Ke Shi, Hongsheng Chen
doaj   +1 more source

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