Results 171 to 180 of about 34,336 (231)

Dynamics of the bacterial replisome

, 2018
All the instructions that regulate all aspects of the life cycle of any living cell on Earth are safely stored in a molecule called DNA. It is therefore a fundamental process for life that the information on the DNA is preserved and faithfully transmitted to the next generation.
openaire   +1 more source

The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein. [PDF]

Nat Commun
Keskitalo S, Zambo B, Malaymar Pinar D, Tuhkala A, Salokas K, Turunen T, Deutsch N, Davey N, Dosztányi Z, Varjosalo M, Gogl G.   +10 more
europepmc   +1 more source

TIPIN coordinates ATM-dependent checkpoint and NF-κB signaling to counteract DNA replication damage from topoisomerase inhibition. [PDF]

Commun Biol
Khan A, Lim JF, Lo N, Patel JA, Haley J, Kim H.   +5 more
europepmc   +1 more source

Mechanistic models of asymmetric hand-over-hand translocation and nucleosome navigation by CMG helicase. [PDF]

Nat Commun
Nagae F, Murata Y, Yamauchi M, Takada S, Terakawa T.   +4 more
europepmc   +1 more source

Structural insights into the exchange mechanism of a replicative DNA polymerase. [PDF]

Nucleic Acids Res
Feng X, Spiering MM, Ruda de Luna Santos A, Benkovic SJ, Li H.   +4 more
europepmc   +1 more source

Redox-sensitive alteration of replisome architecture safeguards genome integrity

Science, 2017
Kumar Somyajit, Rajat Gupta, Hana Sedlackova, K. Neelsen, Fena Ochs, M. Rask, Chunaram Choudhary, J. Lukas   +7 more
semanticscholar   +1 more source

Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation

Proceedings of the National Academy of Sciences of the United States of America, 2017
R. Georgescu, Zuanning Yuan, Lin Bai, Ruda de Luna Almeida Santos, Jingchuan Sun, Dan Zhang, O. Yurieva, Huilin Li, M. O’Donnell   +8 more
semanticscholar   +1 more source

Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus. [PDF]

Nat Commun
Izquierdo-Martinez A, Schäper S, Brito AD, Liao Q, Tesseur C, Sorg M, Botinas DS, Wang X, Pinho MG.   +8 more
europepmc   +1 more source

Speed variations of bacterial replisomes

Speed variations of bacterial replisomes
Replisomes are multi-protein complexes that replicate genomes with remarkable speed and accuracy. Despite their importance, their dynamics is poorly characterized, especially in vivo. In this paper, we present an approach to infer the replisome dynamics from the DNA abundance distribution measured in a growing bacterial population.
openaire  

Always on the Move: Overview on Chromatin Dynamics within Nuclear Processes. [PDF]

Biochemistry
Delvaux de Fenffe CM, Govers J, Mattiroli F.   +2 more
europepmc   +1 more source