Results 201 to 210 of about 34,336 (231)

A conserved phosphorylation mechanism for regulating the interaction between the CMG replicative helicase and its forked DNA substrate. [PDF]

J Biol Chem
Koit S, Tamberg N, Reinapae A, Peil L, Kristjuhan A, Ilves I.   +5 more
europepmc   +1 more source

Four decades of Eukaryotic DNA replication: From yeast genetics to high-resolution cryo-EM structures of the replisome. [PDF]

Proc Natl Acad Sci U S A
Tye BK.
europepmc   +1 more source

Rescuing bacterial genome replication: essential functions to repair a double-strand break and restart DNA synthesis

Winterhalter C, Fenyk S, Murray H.
europepmc   +1 more source

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Replisome pausing in mutagenesis

Chromosoma, 1992
E. coli cells containing a temperature-sensitive dnaE mutation, in the alpha-subunit of holoenzyme DNA polymerase III, do not survive at the restrictive temperature. Such cells may survive in the presence of the pcbA1 mutation, an allele of the gyrB gene. Such survival is dependent on an active DNA polymerase I. Evidence indicates that DNA polymerase I
R E, Moses, A, Byford, J A, Hejna
openaire   +2 more sources

Replisome-Mediated DNA Replication

Annual Review of Biochemistry, 2001
▪ Abstract  The elaborate process of genomic replication requires a large collection of proteins properly assembled at a DNA replication fork. Several decades of research on the bacterium Escherichia coli and its bacteriophages T4 and T7 have defined the roles of many proteins central to DNA replication.
S J, Benkovic, A M, Valentine, F, Salinas   +2 more
openaire   +2 more sources

G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation.

Science
DNA G-quadruplexes (G4s) are non-B-form DNA secondary structures that threaten genome stability by impeding DNA replication. To elucidate how G4s induce replication fork arrest, we characterized fork collisions with preformed G4s in the parental DNA ...
S. Batra, Benjamin Allwein, Charanya Kumar, Sujan Devbhandari, Jan-Gert Brüning, S. Bahng, Chong M Lee, K. Marians, R. Hite, Dirk Remus   +9 more
semanticscholar   +1 more source

Communication between DNA polymerases and Replication Protein A within the archaeal replisome

bioRxiv
Replication Protein A (RPA) plays a pivotal role in DNA replication by coating and protecting exposed single-stranded DNA, and acting as a molecular hub that recruits additional replication factors.
M. Martínez-Carranza, Léa Vialle, C. Madru, F. Cordier, A. Tekpinar, A. Haouz, Pierre Legrand, Rémy A. Le Meur, Patrick England, Rémi Dulermo, J. Iñaki Guijarro, Ghislaine Henneke, L. Sauguet   +12 more
semanticscholar   +1 more source