Results 161 to 170 of about 41,808 (246)

A cardiac sodium channelopathy overlap syndrome presenting as stroke in a young child. [PDF]

HeartRhythm Case Rep
Arumugam P, Handa A, Deepti S, Parakh N, Sharma G, Naik N.   +5 more
europepmc   +1 more source

Prospective in silico trials identify combined SK and K2P channel block as an effective strategy for atrial fibrillation cardioversion

The Journal of Physiology, EarlyView.
Abstract figure legend In silico trials were conducted in 654 virtual patients with atrial fibrillation (AF) to assess the cardioversion efficacy of three pharmacological treatments: single SK and K2P channel block and combined SK+K2P channel inhibition. Left: representative virtual AF patient with the atria inside the torso.
Albert Dasí, Lucas Arantes Berg, Hector Martinez‐Navarro, Alfonso Bueno‐Orovio, Blanca Rodriguez   +4 more
wiley   +1 more source

Successful Isoproterenol Treatment for Ventricular Fibrillation Storm in Early Repolarization Syndrome With SCN5A Mutation. [PDF]

Ann Noninvasive Electrocardiol
Kim SS, Byoun JT, Joo D, Ko JS, Kim NH, Jeong HK.   +5 more
europepmc   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

Exercise-induced abnormal recovery of heart rate and ventricular repolarization parameters among smokers without known cardiovascular disease: A cross-sectional study. [PDF]

Tob Induc Dis
Cosgun A, Oren H.
europepmc   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Spatial and temporal dispersion of ventricular repolarization in pediatric patients with congenital long QT syndrome. [PDF]

HeartRhythm Case Rep
Dai L, Zhang C, Ramdat Misier NL, van Schie MS, Bear L, Haissaguerre M, Taverne YJHJ, de Groot NMS.   +7 more
europepmc   +1 more source

Early Repolarization Syndrome -- Repolarization Abnormality vs. Depolarization Abnormality

Japanese Journal of Electrocardiology, 2012
Tetsushi Furukawa, Akiko Koizumi, Tetsuo Sasano   +2 more
openaire   +2 more sources

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Magnetocardiography for noninvasive surveillance of rejection and cardiac allograft vasculopathy in heart transplant recipients. [PDF]

Am Heart J Plus
Eskander C, Peters M, Gupta D, Bruno KA, Vilaro JR.   +4 more
europepmc   +1 more source