Results 141 to 150 of about 21,330,318 (342)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Denosing Using Wavelets and Projections onto the L1-Ball [PDF]
Both wavelet denoising and denosing methods using the concept of sparsity are based on soft-thresholding. In sparsity based denoising methods, it is assumed that the original signal is sparse in some transform domains such as the wavelet domain and the ...
Cetin, A. Enis, Tofighi, Mohammad
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Council On The Advancement Of Standards
NODA Report
doaj +1 more source
A Framework for Life Cycle Sustainability Assessment of Road Salt Used in Winter Maintenance Operations [PDF]
It is important to assess from a holistic perspective the sustainability of road salt widely used in winter road maintenance (WRM) operations. The importance becomes increasingly apparent in light of competing priorities faced by roadway agencies, the ...
Cui, Na, Shi, Xianming, Xie, Ning
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Trypophobia: What Do We Know So Far? A Case Report and Comprehensive Review of the Literature [PDF]
Juan Carlos Martínez-Aguayo +4 more
openalex +1 more source
Bi-Lipschitz Bijection between the Boolean Cube and the Hamming Ball
We construct a bi-Lipschitz bijection from the Boolean cube to the Hamming ball of equal volume. More precisely, we show that for all even n there exists an explicit bijection f from the n-dimensional Boolean cube to the Hamming ball of equal volume ...
Benjamini, Itai +2 more
core +1 more source

