Results 151 to 160 of about 65,490 (287)

‘Atlantis Buried Outside’: Muriel Rukeyser, Myth and the Crises of War [PDF]

, 2015
Hickman, Ben
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Network Component Analysis Can Identify Potential Axenisation Strategies Circumventing Antibiotic-Use for Phototrophic Eukaryotic Microalgae. [PDF]

Environ Microbiol Rep
Iyer A, Monissen M, Teo Q, Modin O, Halim R.   +4 more
europepmc   +1 more source

Performing Euroscepticism: the UK press and Cameron’s Bloomberg speech [PDF]

, 2015
A Menon, B Hawkins, Belfast Telegraph, C Gifford, C Gifford, C Leconte, C Pentland, D Cameron, D Hannan, F Serricchio, G Wilkes, J Díez Medrano, J FitzGibbon, K Donaldson, K Oppermann, L Price, M Bruter, M Spiering, O Daddow, O Daddow, P Anderson, P Gannon, P Sherrington, P Taggart, R Brookes, R Ford, R Harmsen, R Liddle, S Usherwood, S Vasilopoulou, W Wallace   +30 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Assessment of online newspapers' framing directions of COVID-19 outbreak data in Nigeria. [PDF]

Data Brief
Bamigbolayin-Afolabi F, Oyesomi K, Amodu L, Okorie N, Adesina E, Omale G.   +5 more
europepmc   +1 more source

Improving the prognostic value of multimorbidity through the integration of selected biomarkers to the comprehensive geriatric assessment: An observational retrospective monocentric study. [PDF]

Front Med (Lausanne), 2022
Piacenza F, Di Rosa M, Fedecostante M, Madotto F, Montesanto A, Corsonello A, Cherubini A, Provinciali M, Soraci L, Lisa R, Bustacchini S, Bonfigli AR, Lattanzio F.   +12 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source