Results 191 to 200 of about 2,314 (257)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Apples and oranges? The importance of recognizing heterogeneity in arts and health research publications. [PDF]

Front Public Health
Jensen A, Bungay H, Holt NJ.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Klebsiella pneumoniae-induced liver abscess in a patient with ulcerative colitis: a case report and review of the literature. [PDF]

J Med Case Rep
Chen S, Shi Y, Qi L.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Age-Based Outcomes of Total Arterial Grafting. [PDF]

Ann Thorac Surg Short Rep
Nagi J, Comanici M, Marczin N, Bhudia SK, Raja SG, Cardiac Outcomes Research Group and Initiative (CORGI).   +5 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Hope in sight … Organisational challenges and mental health opportunities for refugee children in school contexts after arriving in an initial reception centre. [PDF]

Front Psychol
Meurs P, Schäfer D, Özkan D, Kulić I, Bär C, Marburger J.   +5 more
europepmc   +1 more source

Missed Nursing Care Infection Prevention and Control Practices in Acute Hospitals in Ireland During the COVID-19 Pandemic. [PDF]

Int J Nurs Pract
Kirwan M, Egan E, Matthews A.
europepmc   +1 more source

Bilateral Morgagni hernia in a Palestinian child with Down syndrome: a rare case report and literature review. [PDF]

Ann Med Surg (Lond)
Abu Hetta A, Shawabka AM, AbuIrayyeh BM, Pujee BK, Alwahsh IM, Eid HI, Thabaineh RW.   +6 more
europepmc   +1 more source