Results 61 to 70 of about 4,208,353 (305)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Challenges of Improving Patient-Centred Care in Parkinson’s Disease

open access: yesJournal of Parkinson’s Disease, 2017
Background: Parkinson’s disease is a neurodegenerative condition with a complex pattern of motor and non-motor symptoms. Of several clinical scales used to measure patient experience few are delivered by patients themselves.
Soania Mathur   +5 more
doaj   +1 more source

Cutaneous plasmacytosis: a case report and review of pulmonary findings

open access: yesDermatology Reports, 2011
Primary cutaneous plasmacytosis is an uncommon cutaneous disorder with multiple cutaneous nodules and plaques mainly on face and trunk. This entity is thought to be a reactive process with unknown etiology.
Weeranut Chantachaeng   +1 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Empirical Illustration of the Hierarchical Organisation of Social Thought: A Domino Effect?

open access: yesInteramerican Journal of Psychology, 2009
The "architecture of social thinking", a model presented by Rouquette (1996) suggests that various forms of social thought may be conceived as being part of a hierarchical organisation.
Rafael Pecly Wolte   +2 more
doaj  

Mind-wandering rates fluctuate across the day: evidence from an experience-sampling study

open access: yesCognitive Research, 2018
Previous research has demonstrated reliable fluctuations in attentional processes during the course of the day. Everyday life experience sampling, during which participants respond to “probes” delivered at random intervals throughout the day on their ...
Gabriel King Smith   +3 more
doaj   +1 more source

Band of mothers: Childbirth as a female bonding experience.

open access: yesPLoS ONE, 2020
Does the experience of childbirth create social bonds among first-time mothers? Previous research suggests that sharing emotionally intense or painful experiences with others leads to "identity fusion," a visceral feeling of oneness with a group that ...
Tara Tasuji   +3 more
doaj   +1 more source

Phase transitions in systems of self-propelled agents and related network models

open access: yes, 2007
An important characteristic of flocks of birds, school of fish, and many similar assemblies of self-propelled particles is the emergence of states of collective order in which the particles move in the same direction. When noise is added into the system,
C. Huepe   +5 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Home accidents amongst elderly people: A locality study in Scotland [PDF]

open access: yes, 2007
Aim The aim of this locality study was to collect information on reported and unreported accidents amongst elderly people living in one locality in Scotland.
Banks, P   +6 more
core  

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