Results 121 to 130 of about 657,091 (294)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

RIT Reporter - May 19th 1959

open access: yes, 1959
Class Of 1959 Congratulated (p. 2); Reporter Rated By College Press (p. 2); 800 to Graduate At War Memorial (p. 2); Alumni President’s Message (p. 2); “Free Day†At Library (p. 2); 1959-60 Reporter Staff Positions Filled (p.
RIT Reporter Staff
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reporter - January 12th 1962

open access: yes, 1962
Printing Week banquet planned (p. 1); Blood drive under way for ’62 at RIT (p. 1); Board appoints committee to supervise institute move (p. 1); Phi Sig schedules winter weekend (p. 1); Printers to hear LTF research director (p.
RIT Reporter Staff
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Hebdomadaires de bandes dessinées et imaginaires médiatiques dans les années 1950–1960

open access: yesComicalités
This article looks at the place of comic strip magazines from the 1950s–1960s in media culture, and more specifically in the history of the press. It shows that, while the hybridity of these periodicals is undeniable, the alternation between editorial ...
Alexis Lévrier
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reporter - November 4th 1960

open access: yes, 1960
A Farewell to Autumn (p. 1); Tuition Increased; $25 Quarterly Hike to Begin Next Year (p. 2); Reporter Rated \u27First Class\u27 By Press Group (p. 2); Election Eve Party Set for Snack Bar On Tuesday Night (p.
RIT Reporter Staff
core  

Report [PDF]

open access: yesDatenschutz und Datensicherheit - DuD, 2021
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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