Results 1 to 10 of about 325,683 (268)
Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus
Microbiology Spectrum, 2022 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the highly contagious agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.
Kevin Chiem +8 more
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Frontiers in Pharmacology, 2023 The dopamine D4 receptor (D4R) is expressed in the retina, prefrontal cortex, and autonomic nervous system and has been implicated in attention deficit hyperactivity disorder (ADHD), substance use disorders, and erectile dysfunction.
Viktor Burström +11 more
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Bioengineering, 2022 Reporter phage assays are a promising alternative to culture-based assays for rapidly detecting viable bacteria. The reporter systems used in phage-based detection are typically enzymes and their corresponding substrates that provide a signal following ...
Shalini Wijeratne +2 more
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Frontiers in Immunology, 2023 Investigations into the strength of antigen-specific responses in vitro is becoming increasingly relevant for decision making in early-phase research of novel immunotherapeutic approaches, including adoptive cell but also immune checkpoint inhibitor (ICI)
Jimena Álvarez Freile +6 more
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Reverse Genetic Approaches for the Generation of Full Length and Subgenomic Replicon of EV71 Virus
Frontiers in Microbiology, 2021 Enterovirus 71 (EV71) is a neurotropic pathogen that causes hand, foot, and mouth disease (HFMD) and it has been consistently associated with severe neurological, cardiac, and respiratory complications.
Hang Yang +5 more
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Using Biosensors to Study Protein–Protein Interaction in the Hippo Pathway
Frontiers in Cell and Developmental Biology, 2021 The Hippo signaling network is dependent on protein–protein interactions (PPIs) as a mechanism of signal transduction to regulate organ size, cellular proliferation and differentiation, tumorigenesis, and other cellular processes.
Alexander Pipchuk, Xiaolong Yang
doaj +1 more source
Pharmaceuticals, 2021 Bioactive plant compounds and extracts are of special interest for the development of pharmaceuticals. Here, we describe the screening of more than 1100 aqueous plant extracts and synthetic reference compounds for their ability to stimulate or inhibit ...
Roland Hager +10 more
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Luciferase-based reporter assay.
, 2021 (A) Luciferase was cloned behind the conJ promoter and transformed into wildtype, the ΔfphA- or the ΔlreA-deletion strains. After 16 h incubation in the dark, luminescence was measured every 10 min for 90 min under the indicated light conditions.
Zhenzhong Yu (5704235) +6 more
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Frontiers in Cellular and Infection Microbiology, 2022 Malaria elimination is dependent on the ability to target both the pathogenic and transmissible stages of the human malaria parasite, Plasmodium falciparum.
Janette Reader +3 more
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Triggering cell death in cancers using self-illuminating nanocomposites
Frontiers in Chemistry, 2022 Bioinspired photocatalysis has resulted in efficient solutions for many areas of science and technology spanning from solar cells to medicine. Here we show a new bioinspired semiconductor nanocomposite (nanoTiO2-DOPA-luciferase, TiDoL) capable of ...
Tijana Rajh +6 more
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