Results 1 to 10 of about 361,847 (262)
NS-segment-based reporter influenza A viruses: engineering strategy, applications, and limitations [PDF]
Journal of VirologyReporter-expressing recombinant influenza A viruses (IAVs) have emerged as powerful tools for studying viral infection, host–pathogen interactions, and the identification and characterization of prophylactic and/or therapeutic countermeasures for the ...
Ramya S. Barre +5 more
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Overview of the reporter genes and reporter mouse models
Animal Models and Experimental Medicine, 2018 AbstractReporter genes are widely applied in biotechnology and biomedical research owning to their easy observation and lack of toxicity. Taking advantage of the reporter genes in conjunction with imaging technologies, a large number of reporter mouse models have been generated. Reporter mouse models provide systems that enable the studies of live cell
Shun Li, Bo-Yin Qin, Xiao-Nan Ren
exaly +3 more sources
Scientific Reports, 2021 Reporter gene assays are widely used to study cellular signaling and transcriptional activity. Few studies describe the use of reporter genes for studying cellular responses on complex body fluids, such as urine and blood.
L W van Rhijn, T J M Welting
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Development and characterization of mouse-adapted recombinant SARS-CoV-2 expressing reporter genes [PDF]
Microbiology SpectrumSARS-CoV-2 is the causative agent of COVID-19. The ancestral SARS-CoV-2 Washington-1 (WA1) strain does not infect standard laboratory mouse strains, necessitating the use of mouse-adapted (MA) viruses.
Sara H. Mahmoud +10 more
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MRI reporter genes in the era of gene transfer
Clinical and Translational Medicine, 2022 Dan Cohen +2 more
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StORF-Reporter: finding genes between genes
Nucleic Acids Research, 2022 Abstract Large regions of prokaryotic genomes are currently without any annotation, in part due to well-established limitations of annotation tools. For example, it is routine for genes using alternative start codons to be misreported or completely omitted.
Nicholas J Dimonaco +4 more
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Replication-Competent ΔNS1 Influenza A Viruses Expressing Reporter Genes
Viruses, 2021 The influenza A virus (IAV) is able to infect multiple mammalian and avian species, and in humans IAV is responsible for annual seasonal epidemics and occasional pandemics of respiratory disease with significant health and economic impacts.
Aitor Nogales +5 more
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Journal of Nuclear Medicine, 2008 Noninvasive molecular imaging of dynamic processes has benefited tremendously from the use of reporter genes. These genes encode for proteins that emit light, bind radiolabeled probes, or, as covered in this review, modulate MRI contrast. Reporter genes play a pivotal role in monitoring cell trafficking, gene replacement therapy, protein-protein ...
Assaf A, Gilad +5 more
openaire +2 more sources
Bi-Reporter Vaccinia Virus for Tracking Viral Infections In Vitro and In Vivo
Microbiology Spectrum, 2021 Recombinant viruses expressing reporter genes allow visualization and quantification of viral infections and can be used as valid surrogates to identify the presence of the virus in infected cells and animal models.
Kevin Chiem +7 more
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Covalent 18F-Radiotracers for SNAPTag: A New Toolbox for Reporter Gene Imaging
Pharmaceuticals, 2021 There is a need for versatile in vivo nuclear imaging reporter systems to foster preclinical and clinical research. We explore the applicability of the SNAPTag and novel radiolabeled small-molecule ligands as a versatile reporter gene system for in vivo ...
Sophie Stotz +4 more
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