Results 11 to 20 of about 355,590 (262)

Abnormal dosage compensation of reporter genes driven by the Drosophila glass multiple reporter (GMR) enhancer-promoter. [PDF]

open access: yesPLoS ONE, 2011
In Drosophila melanogaster the male specific lethal (MSL) complex is required for upregulation of expression of most X-linked genes in males, thereby achieving X chromosome dosage compensation.
Corey Laverty   +3 more
doaj   +1 more source

Reporter Gene Assays [PDF]

open access: yes, 2009
Reporter gene assays are versatile and sensitive methods of assaying numerous targets in high-throughput drug-screening programs. A variety of reporter genes allow users a choice of signal that can be tailored to the required sensitivity, the available detection apparatus, the cellular system employed, and the required compatibility with multiplexed ...
Liu, A.M.F.   +3 more
openaire   +3 more sources

Environmental Application of Reporter-Genes Based Biosensors for Chemical Contamination Screening

open access: yesArchives of Environmental Protection, 2014
The paper presents results of research concerning possibilities of applications of reporter-genes based microorganisms, including the selective presentation of defects and advantages of different new scientific achievements of methodical solutions in ...
Matejczyk Marzena   +1 more
doaj   +1 more source

Multi-color fluorescent reporter dengue viruses with improved stability for analysis of a multi-virus infection. [PDF]

open access: yesPLoS ONE, 2018
Reporter virus is a versatile tool to visualize and to analyze virus infections. However, for flaviviruses, it is difficult to maintain the inserted reporter genes on the viral genome, limiting its use in several studies that require homogeneous virus ...
Amporn Suphatrakul   +6 more
doaj   +1 more source

Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus

open access: yesMicrobiology Spectrum, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the highly contagious agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.
Kevin Chiem   +8 more
doaj   +1 more source

MRI Reporter Genes for Noninvasive Molecular Imaging

open access: yesMolecules, 2016
Magnetic resonance imaging (MRI) is one of the most important imaging technologies used in clinical diagnosis. Reporter genes for MRI can be applied to accurately track the delivery of cell in cell therapy, evaluate the therapy effect of gene delivery ...
Caixia Yang   +3 more
doaj   +1 more source

Replication-Competent Influenza A Viruses Expressing Reporter Genes

open access: yesViruses, 2016
Influenza A viruses (IAV) cause annual seasonal human respiratory disease epidemics. In addition, IAV have been implicated in occasional pandemics with inordinate health and economic consequences.
Michael Breen   +3 more
doaj   +1 more source

A BAC-bacterial recombination method to generate physically linked multiple gene reporter DNA constructs

open access: yesBMC Biotechnology, 2009
Background Reporter gene mice are valuable animal models for biological research providing a gene expression readout that can contribute to cellular characterization within the context of a developmental process.
Gong Shiaochin   +5 more
doaj   +1 more source

Use of Reporter Genes in the Generation of Vaccinia Virus-Derived Vectors

open access: yesViruses, 2016
Vaccinia virus (VACV) is one of the most extensively-studied viruses of the Poxviridae family. It is easy to genetically modify, so it has become a key tool for many applications.
Sally Al Ali   +3 more
doaj   +1 more source

Ectopic T cell receptor-α locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once. [PDF]

open access: yesPLoS ONE, 2010
The molecular mechanisms regulating the activity of the TCRα gene are required for the production of the circulating T cell repertoire. Elements of the mouse TCRα locus control region (LCR) play a role in these processes. We previously reported that TCRα
Stefan Knirr   +7 more
doaj   +1 more source

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