Results 21 to 30 of about 542,740 (308)
, 2009 Reporter gene assays are versatile and sensitive methods of assaying numerous targets in high-throughput drug-screening programs. A variety of reporter genes allow users a choice of signal that can be tailored to the required sensitivity, the available detection apparatus, the cellular system employed, and the required compatibility with multiplexed ...
Liu, A.M.F. +3 more
openaire +3 more sources
Environmental Application of Reporter-Genes Based Biosensors for Chemical Contamination Screening
Archives of Environmental Protection, 2014 The paper presents results of research concerning possibilities of applications of reporter-genes based microorganisms, including the selective presentation of defects and advantages of different new scientific achievements of methodical solutions in ...
Matejczyk Marzena +1 more
doaj +1 more source
CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter. [PDF]
, 2017 The innate immune system protects against infections by initiating an inducible inflammatory response. NF-κB is one of the critical transcription factors controlling this complex response, but some aspects of its regulation remain unclear.
Carpenter, Susan +8 more
core +1 more source
Multi-color fluorescent reporter dengue viruses with improved stability for analysis of a multi-virus infection. [PDF]
PLoS ONE, 2018 Reporter virus is a versatile tool to visualize and to analyze virus infections. However, for flaviviruses, it is difficult to maintain the inserted reporter genes on the viral genome, limiting its use in several studies that require homogeneous virus ...
Amporn Suphatrakul +6 more
doaj +1 more source
Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus
Microbiology Spectrum, 2022 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the highly contagious agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.
Kevin Chiem +8 more
doaj +1 more source
Different 3' end regions strongly influence the level of gene expression in plant cells [PDF]
, 1989 We have investigated the functional role of a 3' end region on the expression of a reporter gene in plant cells. In stably transformed plants, expression of the reporter gene without a plant gene 3' end is variable and depends on the fortuitous presence ...
Ingelbrecht, Ivan +4 more
core +1 more source
MRI Reporter Genes for Noninvasive Molecular Imaging
Molecules, 2016 Magnetic resonance imaging (MRI) is one of the most important imaging technologies used in clinical diagnosis. Reporter genes for MRI can be applied to accurately track the delivery of cell in cell therapy, evaluate the therapy effect of gene delivery ...
Caixia Yang +3 more
doaj +1 more source
The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo [PDF]
, 2005 Maternal and zygotic activities of the homeodomain protein PAL-1 specify the identity and maintain the development of the multipotent C blastomere lineage in the C. elegans embryo. To identify PAL-1 regulatory target genes, we used microarrays to compare
Baugh, L. Ryan +7 more
core +1 more source
Replication-Competent Influenza A Viruses Expressing Reporter Genes
Viruses, 2016 Influenza A viruses (IAV) cause annual seasonal human respiratory disease epidemics. In addition, IAV have been implicated in occasional pandemics with inordinate health and economic consequences.
Michael Breen +3 more
doaj +1 more source
BMC Biotechnology, 2009 Background Reporter gene mice are valuable animal models for biological research providing a gene expression readout that can contribute to cellular characterization within the context of a developmental process.
Gong Shiaochin +5 more
doaj +1 more source