Results 61 to 70 of about 955,297 (305)

A pH-correctable, DNA-based fluorescent reporter for organellar Calcium

open access: yesNature Methods, 2018
It is extremely challenging to quantitate lumenal Ca2+ in acidic Ca2+ stores of the cell because all Ca2+ indicators are pH sensitive, and Ca2+ transport is coupled to pH in acidic organelles.
Nagarjun Narayanaswamy   +6 more
semanticscholar   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine   +17 more
wiley   +1 more source

Orange County Reporter, December 18, 1884 [PDF]

open access: yes, 1884
Orange County Reporter newspaper from February 21, 1884 to December 25, 1884.https://stars.library.ucf.edu/cfm-orangecountyreporter/1049/thumbnail ...
Orange County Reporter
core  

Stable and destabilized GFP reporters to monitor calcineurin activity in Saccharomyces cerevisiae

open access: yesMicrobial Cell, 2020
The protein phosphatase calcineurin is activated in response to rising intracellular Ca2+ levels and impacts fundamental cellular processes in organisms ranging from yeast to humans.
Jutta Diessl   +4 more
doaj   +1 more source

Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform.

open access: yesMolecular Therapy, 2019
Chimeric antigen receptor (CAR)-T cell immunotherapy is under intense preclinical and clinical investigation, and it involves a rapidly increasing portfolio of novel target antigens and CAR designs.
J. Rydzek   +8 more
semanticscholar   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani   +7 more
wiley   +1 more source

Orange County Reporter, February 28, 1884 [PDF]

open access: yes, 1884
Orange County Reporter newspaper from February 21, 1884 to December 25, 1884.https://stars.library.ucf.edu/cfm-orangecountyreporter/1001/thumbnail ...
Orange County Reporter
core  

Advanced Bioluminescence Reporter with Engineered Gaussia Luciferase via Sequence-Guided Mutagenesis

open access: yesBiosensors
Gaussia luciferase (GLuc) is the preeminent secreted luciferase widely used in cell-based reporter assays. By employing sequence-guided mutagenesis informed by alignments of diverse copepod luciferase sequences, we identified key amino acids that ...
Vinayakumar Gedi   +3 more
doaj   +1 more source

Recent technological advances in using mouse models to study ovarian cancer

open access: yesFrontiers in Oncology, 2014
Serous epithelial ovarian cancer (SEOC) is the most lethal gynecological cancer in the United States with disease recurrence being the major cause of morbidity and mortality.
Carrie Danielle House   +2 more
doaj   +1 more source

Molecular Imaging with Reporter Genes: Has Its Promise Been Delivered?

open access: yesJournal of Nuclear Medicine, 2019
The first reporter systems were developed in the early 1980s and were based on measuring the activity of an enzyme—as a surrogate measure of promoter-driven transcriptional activity—which is now known as a reporter gene system.
I. Serganova, R. Blasberg
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy