Results 21 to 30 of about 542,183 (294)

Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts. [PDF]

Nature, 2018
Bourdeau RW, Lee-Gosselin A, Lakshmanan A, Farhadi A, Kumar SR, Nety SP, Shapiro MG.   +6 more
europepmc   +2 more sources

Overview of the reporter genes and reporter mouse models. [PDF]

Animal Model Exp Med, 2018
Li S, Chen LX, Peng XH, Wang C, Qin BY, Tan D, Han CX, Yang H, Ren XN, Liu F, Xu CH, Zhou XH.   +11 more
europepmc   +2 more sources

Reporter Gene Assays [PDF]

, 2009
Reporter gene assays are versatile and sensitive methods of assaying numerous targets in high-throughput drug-screening programs. A variety of reporter genes allow users a choice of signal that can be tailored to the required sensitivity, the available detection apparatus, the cellular system employed, and the required compatibility with multiplexed ...
Liu, A.M.F., New, David C., Lo, Kin H., Wong, Yung Hou   +3 more
openaire   +3 more sources

Adenovirus-mediated gene transfer in primary murine adipocytes

Journal of Lipid Research, 2000
The transfer of genes into primary murine adipocytes using an adenovirus system has been developed. A recombinant adenovirus was constructed (expressing green fluorescent protein [GFP] under the control of the strong cytomegalovirus [CMV] promoter and a ...
Ann Vogel Hertzel, Mark A. Sanders, David A. Bernlohr   +2 more
doaj   +1 more source

CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter. [PDF]

, 2017
The innate immune system protects against infections by initiating an inducible inflammatory response. NF-κB is one of the critical transcription factors controlling this complex response, but some aspects of its regulation remain unclear.
Carpenter, Susan, Covarrubias, Sergio, Fong, Nicholas, Hanley, Nicole, Katzman, Sol, McManus, Michael T, Robinson, Elektra K, Shapleigh, Barbara, Vollmers, Apple   +8 more
core   +1 more source

Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device

Molecular Therapy: Nucleic Acids, 2013
Despite the development of potent siRNAs that effectively target genes responsible for skin disorders, translation to the clinic has been hampered by inefficient delivery through the stratum corneum barrier and into the live cells of the epidermis ...
Robyn P Hickerson, Winston C Wey, David L Rimm, Tycho Speaker, Susie Suh, Manuel A Flores, Emilio Gonzalez-Gonzalez, Devin Leake, Christopher H Contag, Roger L Kaspar   +9 more
doaj   +1 more source

Different 3' end regions strongly influence the level of gene expression in plant cells [PDF]

, 1989
We have investigated the functional role of a 3' end region on the expression of a reporter gene in plant cells. In stably transformed plants, expression of the reporter gene without a plant gene 3' end is variable and depends on the fortuitous presence ...
Ingelbrecht, Ivan, Herman, Lieve MF, Dekeyser, Rudy, Van Montagu, Marc, Depicker, Anna   +4 more
core   +1 more source

Environmental Application of Reporter-Genes Based Biosensors for Chemical Contamination Screening

Archives of Environmental Protection, 2014
The paper presents results of research concerning possibilities of applications of reporter-genes based microorganisms, including the selective presentation of defects and advantages of different new scientific achievements of methodical solutions in ...
Matejczyk Marzena, Rosochacki Stanisław Józef   +1 more
doaj   +1 more source

The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo [PDF]

, 2005
Maternal and zygotic activities of the homeodomain protein PAL-1 specify the identity and maintain the development of the multipotent C blastomere lineage in the C. elegans embryo. To identify PAL-1 regulatory target genes, we used microarrays to compare
Baugh, L. Ryan, Brown, Eugene L., Claggett, Julia M., Hill, Andrew A., Hill-Harfe, Kate, Hunter, Craig P., Slonim, Donna K., Wen, Joanne C.   +7 more
core   +1 more source

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

Stem Cell Reports, 2016
The ability to reliably express fluorescent reporters or other genes of interest is important for using human pluripotent stem cells (hPSCs) as a platform for investigating cell fates and gene function.
Tim Kao, Tanya Labonne, Jonathan C. Niclis, Ritu Chaurasia, Zerina Lokmic, Elizabeth Qian, Freya F. Bruveris, Sara E. Howden, Ali Motazedian, Jacqueline V. Schiesser, Magdaline Costa, Koula Sourris, Elizabeth Ng, David Anderson, Antonietta Giudice, Peter Farlie, Michael Cheung, Shireen R. Lamande, Anthony J. Penington, Clare L. Parish, Lachlan H. Thomson, Arash Rafii, David A. Elliott, Andrew G. Elefanty, Edouard G. Stanley   +24 more
doaj   +1 more source