Results 131 to 140 of about 2,028,694 (277)

Reducing Research Waste Through Good Reporting Practices

Journal of Epidemiology, 2016
Yasuyuki Okumura
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Pengaruh Pengungkapan Sustainability Reporting terhadap Respon Investor [PDF]

, 2015
The study attempts to determine whether sustainability reporting disclosured by Indonesia companies affect investor response. Sustainability reporting is measured based its completeness compared to GRI 3.1 guidelines.
Swenjiadi, J. (Jenawan)
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Interpretation of the "Standards for universal reporting of patient decision aid evaluation studies(SUNDAE)"

Huli yanjiu
To improve the quality and enhance the transparency and completeness of reporting for evaluation studies of patient decision aids,the International Patient Decision Aid Standards(IPDAS) Collaboration Group published the SUNDAE(Standards for universal ...
QIU Yu, HOU Dan, WANG Jianing, LU Xiaoqian   +3 more
doaj  

Did the CDC guidelines for suicide reports affect the New York Times? [PDF]

, 2012
The CDC informed the American media of the best way to avoid contributing to imitative suicides by releasing guidelines for suicide reports in 2001. In this study, suicide reports in the New York Times were examined to establish if these guidelines ...
Marshburn, Joni Kathryn
core   +1 more source

CREDES Reporting Guidelines

Reporting guidelines for Delphi ...
Mohapatra, Sidhiprada, Maiya, G Arun, Nayak, Ullas U, Sheelvant, Rashmi, J, Vennila, Watson, Joanne, Nandineni, Rama Devi   +6 more
openaire   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Guidelines for reporting evaluations based on observational methodology [PDF]

, 2015
Background: Observational methodology is one of the most suitable research designs for evaluating fi delity of implementation, especially in complex interventions.
Anguera Argilaga, María Teresa, Chacón Moscoso, Salvador, Portell Vidal, Mariona, Sanduvete Chaves, Susana   +3 more
core