Results 121 to 130 of about 25,080,468 (342)
ICT Investment and Productivity: A Provincial Perspective [PDF]
In 2008, Statistics Canada, for the first time, made available estimates of information and communication technology (ICT) investment by province.
Andrew Sharpe, Jean-François Arsenault
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Potential Contribution of Aboriginal Canadians to Labour Force, Employment, Productivity and Output Growth in Canada, 2001-2017 [PDF]
Investing in disadvantaged young people is one of the rare public policies with no equity-efficiency tradeoff. This report estimates the potential benefit for the Canadian economy of increasing the educational attainment level of Aboriginal Canadians. We
Andrew Sharpe +2 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Future Productivity Growth in Canada and Implications for the Canada Pension Plan [PDF]
This is organized into three main parts. The first section provides a perspective on future productivity growth in Canada. It discusses key productivity concepts, looks at current productivity trends, examines the forces affecting future productivity ...
Andrew Sharpe
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