Results 81 to 90 of about 3,002,203 (306)
Conference Program: Medical Institutional Repositories in Libraries 2021 (MIRL 2021) [PDF]
, 2021 Program for the Medical Institutional Repositories in Libraries (MIRL 2021) Symposium that took place on Wednesday, November 17 ...
Institutional Repositories in Libraries, Medical
core +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Comparing consortial repositories: a model-driven analysis [PDF]
, 2009 This study aims to provide a comparative assessment of different repository consortia as a reference to inform future work in the area. A review of the literature was used to identify repository consortia, and their features were compared.
Brown, J.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Institutional repositories in New Zealand: comparing institutional strategies for digital preservation and discovery [PDF]
, 2008 This paper outlines an ongoing project to create of a knowledge base to support the development of institutional repositories in New Zealand. The knowledge base wiki includes a summary of key literature to date, highlighting best practice, and standards ...
Chawner, Brenda, Cullen, Rowena
core +1 more source
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2014 This paper presents the project „North +“ for documenting, preserving and providing public access to the cultural heritage in libraries, museums, archives and galleries in North and Central Bulgaria.
Kalina Ivanova +4 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Towards a harmonization of metadata application profiles for agricultural learning repositories [PDF]
, 2008 Metadata interoperability allows the exchange and preservation of crucial learning and teaching information, as well as its future reuse among a large number of different systems and repositories.
Rudgard, Stephen +3 more
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Institutional repositories: review and an information systems perspective [PDF]
, 2006 Purpose: To review the current literature and discussion on institutional repository (IR) and open access (OA) issues, to provide examples from the Information Systems (IS) literature, and to propose the use of IS literature and further research to ...
Wilson, Concepción S. +2 more
core +2 more sources