Results 71 to 80 of about 518,832 (330)

CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis

open access: yesCell Death and Disease, 2021
The chromatin remodeler CHD8, which belongs to the ATP-dependent chromatin remodelers CHD family, is one of the most high-risk mutated genes in autism spectrum disorders.
Song Ding   +7 more
doaj   +1 more source

The preservation and sustainability of research data [PDF]

open access: yes, 2007
This talk is based in part on a survey carried out for APSR and APAC in 2006, which led to the AERES report (http://www.apsr.edu.au/publications/projects.htm) The survey looked at the issues surrounding the management and preservation of a large range of
Australian Partnership for Sustainable Repositories (APSR)
core  

Taking the C out of CVMFS [PDF]

open access: yes, 2012
The Cern Virtual Machine File System is most well known as a distribution mechanism for the WLCG VOs@@ experiment software; as a result, almost all the existing expertise is in installing clients mount the central Cern repositories. We report the results
Doherty, Thomas   +2 more
core   +1 more source

Centralized mouse repositories [PDF]

open access: yesMammalian Genome, 2012
Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited.
Donahue, Leah Rae   +12 more
openaire   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Unusual Events in GitHub Repositories

open access: yes, 2018
In large and active software projects, it becomes impractical for a developer to stay aware of all project activity. While it might not be necessary to know about each commit or issue, it is arguably important to know about the ones that are unusual.
Aniche, Maurício   +2 more
core   +1 more source

Show me the data: the pilot UK Research Data Registry [PDF]

open access: yes, 2014
The UK Research Data (Metadata) Registry pilot project is implementing a prototype registry for the UK's research data assets, enabling the holdings of subject-based data centres and institutional data repositories alike to be searched from a single ...
Ashley, Kevin   +4 more
core   +7 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Taking stock of open access : progress and issues [PDF]

open access: yes, 2006
Purpose - Aims at providing a broad overview of some of the issues emerging from the growth in open access publishing, with specific reference to the use of repositories and open access journals.
McCulloch, E.
core   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

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