Results 51 to 60 of about 3,082,583 (234)
Behaviours and Technical Recommendations of the COAR Next Generation Repositories Working Group: Report [PDF]
, 2017 The widespread deployment of repository systems in higher education and research institutions provides the foundation for a distributed, globally networked infrastructure for scholarly communication.
the Confederation of Open Access Repositories (COAR) +1 more
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
The ETH Zurich DOI Desk: DOIs as standard persistent identifier and best practice in Swiss Open Access repositories [PDF]
, 2014 Presentation at Open Repositories 2014, Helsinki, Finland, June 9-13, 2014General Track Papers and PanelsThe session was recorded and is available for watching (this presentation starts at 1:16:30)Over the last couple of years it has become best practice
Hirschmann, Barbara; id_orcid +1 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Open access journals and institutional repositories: practical need and present trends in India [PDF]
, 2008 Discusses the trends in open access publishing in India. Study is based on data collected from directories of open access journals and institutional repositories.
Devib, Maya +3 more
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
OPEN ACCESS REPOSITORIES: THE ASIAN SCENARIO WITH SPECIAL REFERENCE TO LIBRARY & INFORMATION SCIENCE [PDF]
, 2012 Higher education institutions all over the world are experiencing the necessity of managing their education, research and resources in a more effective way.
Sengupta, Shantashree
core
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source