Results 41 to 50 of about 518,832 (330)

OAIS as a reference model for repositories : an evaluation [PDF]

open access: yes, 2006
The purpose of this document is to evaluate "whether OAIS is an appropriate reference model for use across the variety of repositories being developed within the JISC community" (Campbell 2005, p. 11).
Allinson, Julie
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Open Science Support as a Portfolio of Services and Projects: From Awareness to Engagement

open access: yesPublications, 2018
Together with many other universities worldwide, the University of Göttingen has aimed to unlock the full potential of networked digital scientific communication by strengthening open access as early as the late 1990s.
Birgit Schmidt   +9 more
doaj   +1 more source

Overlay journals, repositories and the evolution of scholarly communication [PDF]

open access: yes, 2010
This paper examines the part overlay journals can play in developing new roles for repositories in the scholarly communication process. This requires that we answer some outstanding questions about the overlay journal model: · How are overlay journals
Brown, J.A.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Licensing Revisited: Open Access Clauses in Practice

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2012
Open access increases the visibility and use of research outputs and promises to maximize the return on our public investment in research. However, only a minority of researchers will "spontaneously" deposit their articles into an open access repository.
Birgit Schmidt, Kathleen Shearer
doaj   +1 more source

My repository is being aggregated: a blessing or a curse? [PDF]

open access: yes, 2014
Usage statistics are frequently used by repositories to justify their value to the management who decide about the funding to support the repository infrastructure.
Anastasiou, Lucas   +2 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Optimising metadata workflows in a distributed information environment [PDF]

open access: yes, 2005
The different purposes present within a distributed information environment create the potential for repositories to enhance their metadata by capitalising on the diversity of metadata available for any given object.
Barton, Jane, Robertson, R. John
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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