Results 121 to 130 of about 6,700,245 (291)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Operation and experiences of the second generation of the Schengen evaluation system
Belügyi SzemleAim: This study aims to explore and summarise nearly a decade of the operations of the second-generation Schengen evaluations, along with the direct experiences related to its implementation.
Lénárd Zsákai
doaj +1 more source
Σύγκριση, 2002 Ακολουθώντας τις καθιερωμένες μεταφορές που περιγράφουν τη μετάφρασημε ερμηνευτικούς όρους, ως τη μεταβίβαση και ανάκτηση ενός κατά ταάλλα απροσπέλαστου νοήματος, το άρθρο προτείνει να κοιτάξουμε πέρα απόαυτή τη συμβατική αυτοπαρουσίαση και να επικεντρωθούμε στην υβριδική,πλουραλιστική φύση των μεταφρασμένων κειμένων" προτείνει ακόμη να εστιάσουμετην ...
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
ARCHive-SRThe study we present is related to a scan-to-BIM process carried out on the Romanesque-Byzantine church of San Giovannello, located in the historic center of Gerace (Reggio Calabria, Italy). The work is part of a broader research project, called GENESIS
Marinella Arena +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source