Results 121 to 130 of about 3,024,688 (292)

Descriptive Geometry: A Question of ‘Form’

open access: yesDisegnare con
What future for Descriptive Geometry? This question is the starting point for a reflection on the role of this discipline in contemporary research and education, focusing on one of its founding objectives: the study of the geometric properties of figures
Leonardo Baglioni, Marta Salvatore
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A comparison of the EU and AU in the field of peace and security – partners and rivals?

open access: yesJournal of Central and Eastern European African Studies
The intention of this paper is to examine how the European Union and the African Union are developing in parallel as voluntary integration projects, and how they compare with regard to the respective development of their defence policies, Union level ...
Katalin Horvath
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Representability ofGL E

open access: yesProceedings Mathematical Sciences, 2002
3 pages ...
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The system of EU situational pictures showing the current state of the Schengen area

open access: yesBelügyi Szemle
Aim: The aim of the study is to review the new system of common situational pictures and risk analyses, in line with the ambitions of the EU to strengthen the governance of the Schengen area, and to explore and introduce the different indicators related
Lénárd Zsákai
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Integrating Building Information Modeling for Enhanced Efficiency and Sustainability in Public Construction: The Sapienza University Protocol

open access: yesHeritage
BIM represents a significant step towards digitalization and innovation in the public construction sector in Italy, and as of 1 January 2025, its adoption became mandatory for all public work.
Martina Attenni   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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