Results 61 to 70 of about 1,628,036 (248)
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
ACHIEVEMENTS OF THE FIRM EGES IN PRODUCTION OF FURNACE SYSTEMS
The modern developments of the firm EGES of induction mid-frequency furnaces are ...
F. Koch, A. M. Shtypa
doaj
The ‘Trio Presidency’ of the Council of the European Union: Towards More Continuity?
This article addresses the Council presidency trio mechanism codified in the Lisbon Treaty with a particular focus on the continuity question in the Council's decision-making framework.
Raik Ele
doaj +1 more source
Triplet Loss Network for Unsupervised Domain Adaptation
Domain adaptation is a sub-field of transfer learning that aims at bridging the dissimilarity gap between different domains by transferring and re-using the knowledge obtained in the source domain to the target domain.
Imad Eddine Ibrahim Bekkouch +4 more
doaj +1 more source
On the explicit representation of the trace space $$H^{\frac{3}{2}}$$ and of the solutions to biharmonic Dirichlet problems on Lipschitz domains via multi-parameter Steklov problems [PDF]
Pier Domenico Lamberti, Luigi Provenzano
openalex +1 more source
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Women and academic medicine: a review of the evidence on female representation [PDF]
Maryse Penny +3 more
openalex +1 more source

