Results 71 to 80 of about 378,256 (262)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Several studies deal with representation of the European Union (EU), but none of them analyzes the views of the contemporary Others of the EU. This study tries to fill this gap and to expand the post-nationalist approach to studying the EU with data ...
Melita Poler Kovačič, Karmen Erjavec
doaj
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Visualising the Imageless Past: Film and Audio-Visual Media in Archaeological Museums
This paper focuses on the use of film and audio-visual media in an exhibition context, as a means for mediating the objects of culture on display, which in turn supports the narration of the exhibition.
Andrea Haller
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Cross-Game Look at Transgender Representation in Video Games
Despite a history of tracking, analyzing, and discussing transgender representation in media, research on video games is often left out. In this project, I analyzed 63 games released from 1988–2019, and documented on the LGBTQ Game Archive as having ...
Hibby Thach
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Roma Minority in Romania and its Media Representation
The aim of this paper is to put into light main aspects of the relationship between the image of Roma as perceived by the majority of population and its representation in the Romanian press from 1990 until 2006. The representation of Roma is considered a
Gabriela Creţu
doaj

