Results 111 to 120 of about 4,861,762 (407)

Locating the ‘radical’ in 'Shoot the Messenger' [PDF]

open access: yes, 2013
This is the author's accepted manuscript. The final published article is available from the link below, copyright 2013 @ Edinburgh University Press.The 2006 BBC drama Shoot the Messenger is based on the psychological journey of a Black schoolteacher, Joe
Ang I.   +11 more
core   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Politics of Interest, Politics of Care: Representation and “Women’s Singularity”

open access: yesRevista Estudos Feministas, 2001
This article discusses different strategies for justifying the adoption of sex-based electoral quotas, emphasizing the type that claim a different moral status for women.
Luís Felipe Miguel
doaj  

O bacharel em direito como o homem público brasileiro

open access: yesMediações: Revista de Ciências Sociais, 2003
Law bachelors are, and always have been, the most widely represented class in brazilian politics. The constitution of the House of Representatives throughout history has reflected this reality since the Empire.
Humberto Dantas
doaj   +1 more source

An axiomatic theory of political representation [PDF]

open access: yesJournal of Economic Theory, 2009
We discuss the theory of voting rules which are immune to gerrymandering. Our approach is axiomatic. We show that any rule that is unanimous, anonymous, and representative consistent must decide a social alternative as a function of the proportions of agents voting for each alternative, and must either be independent of this proportion, or be in one-to-
openaire   +5 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Representation of identities and the politics of representation in cognition

open access: yesAlfa: Revista de Lingüística, 2001
<p>In this paper, I make a plea for viewing representation as first and foremost a political matter. I argue that by so doing we may avoid the many of pitfalls of contemporary theories of cognition as they attempt to tackle the issue of ...
Kanavillil Rajagopalan
doaj  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Making differences: cities, NGOs and the cultural politics of development discourse [PDF]

open access: yes, 2002
This book chapter reveals the politics of representation underlying depictions of non-Western cities in the literature on third world development. Development discourse is preoccupied with imaginary differences and hierarchies, it argues, and the places ...
O'Coill, Carl
core  

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

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