Results 41 to 50 of about 4,904,875 (375)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Descriptive Representation and the Political Engagement of Women
Politics & Gender, 2020 When women are represented on the campaign trail and in elected office, women in the electorate have been shown to report greater engagement in politics.
Jennifer Wolak
semanticscholar +1 more source
Aesthetics relation between art, culture, politics: social turn [PDF]
, 2016 Рукопись поступила в редакцию 1 июня 2016 г.This article deals with the problem of important social turn in the relationship between politics and art in the contemporary situation. In the postmodern sense, the relation between politics and art is assumed
Šuvaković, M.
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
School-based parents’ groups - a politics of voice and representation? [PDF]
, 2000 In this paper we consider two discussion-based parents’ forums at two secondary schools. We ask whether such forums can be considered as part of the small, local associative mechanisms which theorists claim have the potential to encourage a more vibrant ...
Martin, Jane, Vincent, Carol
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Barbarossa − Bar(bar)ossa − Barbossa: The permanence of the Black Legend as a discourse of otherness
Chasqui, 2018 This article explores contemporary cultural appropriations of the Black Legend, a 16th and 17th century narrative used as a propagandistic strategy addressed to criticize Spain’s imperial mission in America.
Salvador Leetoy, Miguel Vázquez Liñán
doaj +1 more source
Risk-talk: the politics of risk and its representation [PDF]
, 2000 Looking at the concept of risk from a cross-cultural perspective, the contributors challenge the Eurocentric frameworks within which notions of risk are more commonly considered. They argue that perceptions of danger, and sources of anxiety, are far more
Vera-Sanso, Penny
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source