Results 51 to 60 of about 2,531,593 (291)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Reseña del Libro de S. Tormey "The End of Representative Politics"
Recerca: Revista de Pensament i Anàlisi, 2017 Simon Tormey’s book, The End of Representative Politics, draws on his work on representation from the last decade as well as on a case study of the tumultuous, but exciting, Spanish politics of recent years. Tormey is interested in a new form of politics
Lasse Thomassen
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Muslim Women and the Politics of Representation
American Journal of Islam and Society, 2002 This paper examines the politics of knowledge production as it relates to Muslim women in western literar y traditions and contemporary feminist writing, with a view to understanding the political, ideological, and economic mediations that have ...
Jasmin Zine
doaj +3 more sources
Barbarossa − Bar(bar)ossa − Barbossa: The permanence of the Black Legend as a discourse of otherness
Chasqui, 2018 This article explores contemporary cultural appropriations of the Black Legend, a 16th and 17th century narrative used as a propagandistic strategy addressed to criticize Spain’s imperial mission in America.
Salvador Leetoy, Miguel Vázquez Liñán
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
VI Zverev International Conference at RSUH “Collective Memory: Power of the Past in Socio-Cultural Life in the USA” [PDF]
Литература двух Америк, 2019 The review outlines the major topics of the conference on the American Studies held by the Russian State University for the Humanities in May 2019.
Victoria I. Zhuravleva +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Power, Politics and Appeasement: Political Realism in British International Thought, 1935-1955
, 2006 The definitive version is available at www.blackwell-synergy.comArticle first published online: 10 NOV 2005as been argued that the failure of 'realist' international thought to take root in Britain in the aftermath of the Second World War, as it did in ...
Hall, Ian +3 more
core +1 more source