Results 41 to 50 of about 18,345 (258)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Reseña del Libro de S. Tormey "The End of Representative Politics"

Recerca: Revista de Pensament i Anàlisi, 2017
Simon Tormey’s book, The End of Representative Politics, draws on his work on representation from the last decade as well as on a case study of the tumultuous, but exciting, Spanish politics of recent years. Tormey is interested in a new form of politics
Lasse Thomassen
doaj  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Televizyonda Dinsel Siyaset: Dini İçerikli Dizilerin Kamusal Alan Projesinde Kadın veya Erkek Olmak [PDF]

Alternatif Politika, 2009
In this study, I will argue for the critical value of politics of representation in a current time that witnesses rapid development in electronic communication mediums together with significant transitions in conceptualization of public sphere ...
Çağlar Enneli
doaj  

Democracy and Continuing Marginalization of Women in Indonesian Politics

E3S Web of Conferences, 2018
Although much progress and efforts have been made to increase women’s participation in politics, the main idea of women’s involvement in politics has not yet penetrated into the mainstream of Indonesian politics.
Hara Abubakar Eby, Trihartono Agus, Viartasiwi Nino   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Immigrant Representation in the Swedish Parliament: Towards Homogeneity or United Diversity?

Social Change Review, 2016
The current study explores how immigrants are represented within the two largest political parties in Sweden, the Social Democratic Party and the Moderate Party. Apart from exploring the descriptive representation of immigrants in the Swedish parliament,
Magnusdottir Gunnhildur Lily
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Muslim Women and the Politics of Representation

American Journal of Islam and Society, 2002
This paper examines the politics of knowledge production as it relates to Muslim women in western literar y traditions and contemporary feminist writing, with a view to understanding the political, ideological, and economic mediations that have ...
Jasmin Zine
doaj   +3 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source