Results 51 to 60 of about 16,767 (236)
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Network Localization of Fatigue in Multiple Sclerosis
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
O bacharel em direito como o homem público brasileiro
Law bachelors are, and always have been, the most widely represented class in brazilian politics. The constitution of the House of Representatives throughout history has reflected this reality since the Empire.
Humberto Dantas
doaj +1 more source
Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Politics of Interest, Politics of Care: Representation and “Women’s Singularity”
This article discusses different strategies for justifying the adoption of sex-based electoral quotas, emphasizing the type that claim a different moral status for women.
Luís Felipe Miguel
doaj
Women Politicians and Parliamentary Elections in Ukraine and Georgia in 2012
: Post-communist countries undergoing social transformations in the last twenty years needed to implement political and economic reforms. Changes also had to support the principles of equality in the access to power, specifically gender quotas in ...
Tetiana Kostiuchenko +2 more
doaj +1 more source
POLITICAL REPRESENTATION IN COMPARATIVE POLITICS [PDF]
▪ Abstract Two large research programs have analyzed election-based connections between citizens and policy makers in different democracies. Studies of vote-seat representation in the tradition of Rae (1967) begin with citizens' party votes and have made substantial progress in elucidating the impact of election laws, geographic vote distributions ...
openaire +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Representation of identities and the politics of representation in cognition
<p>In this paper, I make a plea for viewing representation as first and foremost a political matter. I argue that by so doing we may avoid the many of pitfalls of contemporary theories of cognition as they attempt to tackle the issue of ...
Kanavillil Rajagopalan
doaj

