Results 121 to 130 of about 389,895 (267)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

IntroSurvey of representation theory

open access: yes, 2022
There could be thousands of Introductions/Surveys of representation theory, given that it is an enormous field. This is just one of them, quite personal and informal.
Libedinsky, Nicolas
core  

Representation theory of solitons

open access: yesJournal of High Energy Physics
Solitons in two-dimensional quantum field theory exhibit patterns of degeneracies and associated selection rules on scattering amplitudes. We develop a representation theory that captures these intriguing features of solitons.
Clay Córdova   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Combinatorics, invariant theory and representation theory of symmetric groups

open access: yes, 1984
SIGLECopy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Stoetzer, F. (comp.)   +1 more
core  

Chern-Simons theory, Ehrhart polynomials, and representation theory

open access: yesJournal of High Energy Physics
The Hilbert space of level q Chern-Simons theory of gauge group G of the ADE type quantized on T 2 can be represented by points that lie on the weight lattice of the Lie algebra g up to some discrete identifications.
Chao Ju
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Various topics in representation theory

open access: yes, 1990
SIGLETIB Hannover: RO 236(33) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Bayreuth Univ. (Germany). Mathematisches Inst
core  

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