FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
A robust E learning recommendation system based on novel interval valued bipolar fuzzy hypersoft set theory. [PDF]
Sci RepHarl MI +4 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Quantum Gravity Spacetime: Universe vs. Multiverse. [PDF]
Entropy (Basel)Tessarotto M, Cremaschini C.
europepmc +1 more source
An extension of the localist representation theory: grandmother cells are also widely used in the brain. [PDF]
Front Psychol, 2013 Roy A.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Elevating the allied health professions workforce: leadership's role in shaping professional identity. [PDF]
BMC Health Serv ResHales P, Achour N, King O, Engward H.
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Editorial: Disciplinary Theory & Integrated Representation
Journal of Intelligent Systems, 1994 Dodd, J., Thomas, P.
doaj +1 more source
Phase Behavior and Percolation of a Primitive Model of Laponite Suspension: Wertheim's Thermodynamic Perturbation Theory with Anisotropic Reference Particles. [PDF]
ACS OmegaKalyuzhnyi YV.
europepmc +1 more source