Results 131 to 140 of about 153,246 (202)

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we used mathematical modelling to explore the effect of diabetes on muscle mechanoenergetics. Our parameterisation of cross‐bridge models using data from non‐diabetic and diabetic human atrial tissues revealed lower values for cross‐bridge stiffness, detachment rates, attachment rates and lower ATP sensitivity in ...
Julia H. Musgrave   +4 more
wiley   +1 more source

On computing local monodromy and the numerical local irreducible decomposition

open access: yesTransactions of the London Mathematical Society, Volume 13, Issue 1, December 2026.
Abstract Similarly to the global case, the local structure of a holomorphic subvariety at a given point is described by its local irreducible decomposition. Geometrically, the key requirement for obtaining a local irreducible decomposition is to compute the local monodromy action of a generic linear projection at the given point, which is always well ...
Parker B. Edwards   +1 more
wiley   +1 more source

Equivariant toric geometry and Euler–Maclaurin formulae

open access: yesCommunications on Pure and Applied Mathematics, Volume 79, Issue 3, Page 451-557, March 2026.
Abstract We first investigate torus‐equivariant motivic characteristic classes of toric varieties, and then apply them via the equivariant Riemann–Roch formalism to prove very general Euler–Maclaurin‐type formulae for full‐dimensional simple lattice polytopes.
Sylvain E. Cappell   +3 more
wiley   +1 more source

Words and Meters: Neural Evidence for a Connection Between Individual Differences in Statistical Learning and Rhythmic Ability in Infancy

open access: yesDevelopmental Science, Volume 29, Issue 2, March 2026.
ABSTRACT Music and language are both hierarchically structured: syllables combine into words, and meters are groupings of musical beats. Statistical learning (SL) supports speech segmentation through computation of transitional probabilities between syllables, and individual differences in SL ability were found predictive of further language ...
Iris van der Wulp   +2 more
wiley   +1 more source

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