Results 71 to 80 of about 73,999 (368)
Spatial Representation: Maps of Fragmented Space [PDF]
Current Biology, 2015 Grid cells in medial entorhinal cortex are thought to act as a neural metric for spatial navigation. A new study has examined the ability of grid cells to use self-motion cues to form a global map across fragmented spaces.
openaire +2 more sources
Semantic Hierarchy Emerges in Deep Generative Representations for Scene Synthesis [PDF]
International Journal of Computer Vision, 2019 Despite the great success of Generative Adversarial Networks (GANs) in synthesizing images, there lacks enough understanding of how photo-realistic images are generated from the layer-wise stochastic latent codes introduced in recent GANs.
Ceyuan Yang, Yujun Shen, Bolei Zhou
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
London in space and time: Peter Ackroyd and Will Self [PDF]
, 2013 Copyright @ 2013 the author. This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License.This paper explores the treatment of London by two authors who are profoundly influenced by the concept of the ...
Green, A
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Unsupervised spatially embedded deep representation of spatial transcriptomics
Genome MedicineAbstractOptimal integration of transcriptomics data and associated spatial information is essential towards fully exploiting spatial transcriptomics to dissect tissue heterogeneity and map out inter-cellular communications. We present SEDR, which uses a deep autoencoder coupled with a masked self-supervised learning mechanism to construct a low ...
Hang Xu +13 more
openaire +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
"Real Places in Virtual Spaces" [PDF]
, 2006 Despite what might seem to be the case, "Virtual" reality can be used to create fully "real" places with their own grammar and norms, where real events take ...
Kolb, David
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
GeoTextos, 2013 The present article aims at analyzing the spatiality proposed by the art exhibition “2012: propositions for the future”, taken place at the Museum of Contemporary Art in Curitiba/ Brazil.
Sibele Paulino
doaj