Results 51 to 60 of about 167,447,858 (248)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Échange de passe et lutte de places dans Max Winson de Jérémie Moreau
Comicalités, 2017 The two comic books which compose the series Max Winson by Jeremie Moreau are intended to tell a young and exceptionnal tennis champion’s life. The two books propose numerous representations of stadiums and depict the « exchanges » that the hero has with
Christophe Meunier
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
josef: Spatiality as a Material Property of Audiovisual [PDF]
Soundcloud link: josef Supplementary links to performances of josef: Iklectik 23/04/2022 / EIS 16/06/2022 josef is an audiovisual performance piece composed specifically for an immersive surround sound environment. Throughout every stage of its creative
Wolstanholme, Lewis +3 more
core +1 more source
Bulletin of Geography. Socio-Economic Series, 2018 Increased commercial interest in wild berries in Northern Sweden’s resource periphery has connected places and people to a global berry supply chain that produces goods for world markets.
Eriksson Madeleine, Tollefsen Aina
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Representations of swine flu: Perspectives from a Malaysian pig farm [PDF]
, 2011 © The Author(s), 2010. This is the author's accepted manuscript. The final published article is available from the link below.Novel influenza viruses are seen, internationally, as posing considerable health challenges, but public responses to such ...
Hassan, SBS +7 more
core +1 more source
Confins, 2018 The municipality of São Paulo (MSP) inside the metropolitan region is the largest urban complex in Latin America, with a population of approximately 12 million inhabitants.
Marilia Araujo Roggero +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source