Results 51 to 60 of about 569 (261)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Échange de passe et lutte de places dans Max Winson de Jérémie Moreau

open access: yesComicalités, 2017
The two comic books which compose the series Max Winson by Jeremie Moreau are intended to tell a young and exceptionnal tennis champion’s life. The two books propose numerous representations of stadiums and depict the « exchanges » that the hero has with
Christophe Meunier
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

The production of the rural landscape and its labour: The development of supply chain capitalism in the Swedish berry industry

open access: yesBulletin of Geography. Socio-Economic Series, 2018
Increased commercial interest in wild berries in Northern Sweden’s resource periphery has connected places and people to a global berry supply chain that produces goods for world markets.
Eriksson Madeleine, Tollefsen Aina
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Vulnerabilidade socioambiental, análise de situação de saúde e indicadores: implicações na qualidade de vida no município de São Paulo

open access: yesConfins, 2018
The municipality of São Paulo (MSP) inside the metropolitan region is the largest urban complex in Latin America, with a population of approximately 12 million inhabitants.
Marilia Araujo Roggero   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

“There’s never any ending to Paris” Creating a Literary Myth: Geocritical Aspects of the Works of the Lost Generation

open access: yesVestnik za Tuje Jezike, 2015
This essay proposes to present and analyse the pictures or representations of Paris in Ernest Hemingway’s, Francis Scott Fitzgerald’s and Gertrude Stein’s different works.
Krisztina Sárdi
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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