Results 21 to 30 of about 503,651 (294)
Demokracja bezpośrednia w Austrii – praktyka i perspektywy rozwoju
Politeja, 2023 DIRECT DEMOCRACY IN AUSTRIA – PRACTICE AND DEVELOPMENT PROSPECTS First, the article traces the historical development of and legal regulations related to the instruments of direct democracy in the Second Republic.
Justyna Miecznikowska-Jerzak
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Deliberativa, diretta o partecipativa?
Quaderni di Sociologia, 2014 Representative democracy is currently challenged in all Western political systems. In Italy this challenge in recent years has been launched in a distinctive way by the Movimento Cinque Stelle (M5s, Five Star Movement).
Antonio Floridia, Rinaldo Vignati
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Representation through deliberation-The European case [PDF]
, 2011 This article shows that the main pattern of European democratization has unfolded along the lines of an EU organized as a multilevel system of representative parliamentary government and not as a system of deliberative governance as the transnationalists
Eriksen, Erik O., Fossum, John Erik
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Czech Journal of International Relations, 2021 Representative democracy is beset by a crisis of legitimacy across the world, but in Europe this crisis is compounded by the inadequacy of national governments to address citizens’ frustrations and to achieve transnational unity on common issues.
Horler, Vanessa
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
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Proxy of democracy? : metaphors of connection as arguments against representation [PDF]
, 2012 This paper aims to assess the arguments that claim representative democracy may be enhanced or replaced by an updated electronic version. Focusing on the dimension of elections and electioneering as the core mechanism of representative democracy I will ...
Cuono, Massimo
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source