Results 81 to 90 of about 424,116 (333)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Modernization Without Change: Decision-Making Process in the Mercosur Parliament [PDF]
Brazilian Political Science Review, 2016 This article analyzes the role of Mercosur's Parliament within Mercosur’s institutional design and decision-making process by associating its institutional arrangements to potential outcomes over representativeness.
Marcelo de Almeida Medeiros +2 more
doaj
Representativeness of the FADN CZ sample of agricultural enterprises and ways of its verification
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013 Following accession to the European Union, Czech Republic joined the EU FADN system. The Farm Accountancy Data Network (FADN) is the main EC information source on real economic situation of agricultural enterprises.
Marie Prášilová +2 more
doaj +1 more source
Possible errors in establishing the sample dimensions of survey investigations [PDF]
Starting from the „rough” use of 1,500-1,800 subject samples in field researches with populations of the dimensions of a medium town, a capital or an entire country, which generates doubts and possible questions related to the representativeness of the ...
Alexandru ISAIC-MANIU, Irina M. DRĂGAN
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
CIRCULAR WOOD CONSTRUCTION - EXPECTATIONS, EXPERIENCES AND ACCEPTANCE AMONG USERS, ARCHITECTS AND INDUSTRY REPRESENTATIVES [PDF]
, 2023 Kaja Mathilde Aamodt Heltorp +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source