Results 111 to 120 of about 2,327,108 (281)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Civil Society Report to the Commission on Social Determinants of Health
Social Medicine, 2007 A hundred and fifty years after his death we continue to be reminded of Virchow’s comment: “Do we not always find the diseases of the populace traceable to defects in society”?
Representatives of Civil Society
doaj
Research in the School of the Arts [PDF]
, 2015 Presented and discussed my research role within the School of the Arts with court members (Governors of the University, honorary degree holders, honorary fellows, local employers, representatives of livery companies, local politicians and community ...
Allwork, Larissa
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cleaning OCR'd text with Regular Expressions
The Programming Historian, 2013 Optical Character Recognition (OCR)—the conversion of scanned images to machine-encoded text—has proven a godsend for historical research. This process allows texts to be searchable on one hand and more easily parsed and mined on the other. But we’ve all
Laura Turner O'Hara
doaj
Cogent EducationThis study aims to provide a critical examination of how English as a Second Language (ESL) teachers in primary classrooms in Malaysia utilise the phonics approach when teaching reading.
Azyan Shafee +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Are union representatives badly paid? Evidence from France [PDF]
In this paper, I study the wage differential between firms' union representatives and their coworkers using a linked employer-employee dataset. On the employee side of the data, the surveyed workers are asked if they are unionized but we do not know ...
Thomas Breda
core