Information transmission in a two-step cascade: Interplay of activation and repression [PDF]
We present an information-theoretic formalism to study signal transduction in four architectural variants of a model two-step cascade with increasing input population. Our results categorize these four types into two classes depending upon the effect played out by activation and repression on mutual information, net synergy, and signal-to-noise ratio ...
arxiv
Mathematical modeling of microRNA-mediated mechanisms of translation repression [PDF]
MicroRNAs can affect the protein translation using nine mechanistically different mechanisms, including repression of initiation and degradation of the transcript. There is a hot debate in the current literature about which mechanism and in which situations has a dominant role in living cells.
arxiv +1 more source
Leadership Strategies of Mobilisation and Demobilisation in Sudan
A Sudanese Revolution overthrew the sitting regime in 2019, and a transitional government is in place. This article explores Sudanese respondents’ take on how the former regime managed to stay in power for so long.
Sigrun Marie Moss
doaj +1 more source
Lambda-prophage induction modeled as a cooperative failure mode of lytic repression [PDF]
We analyze a system-level model for lytic repression of lambda-phage in E. coli using reliability theory, showing that the repressor circuit comprises 4 redundant components whose failure mode is prophage induction. Our model reflects the specific biochemical mechanisms involved in regulation, including long-range cooperative binding, and its detailed ...
arxiv +1 more source
Discussion on Psychology Graduate Leading to its Curricular Addressing
Although the revision and updating process on psychology graduation has endured some decades in Brazil, it seems to be nearing its end.
Armando Rocha Junior
doaj
Psychological underpinning of personalized approaches in modern medicine: syndrome analysis of mitral valve prolapsed patients [PDF]
The article aims to demonstrate a high efficiency of the methodological means suggested by psychological syndrome analysis approach (Vygotsky-Luria school) for solving theoretical and applied issues in contemporary person-centered medicine.
Zinchenko, Yury P.+2 more
doaj
Pulsão, afeto e paixão: psicanálise e semiótica Pulsión, afecto y pasión: psicoanálisis y semiótica Drive, affect and passion: psychoanalysis and semiotics
Este artigo apresenta um estudo das premissas e hipóteses liminares, como também as dificuldades de uma pesquisa mais ampla a respeito, que se elabora na interface teórica entre a metapsicologia freudiana (pulsão e afeto) e a semiótica (das paixões).
Waldir Beividas
doaj +1 more source
Background: Repression is considered as a central defense mechanism in psychodynamic theory. It refers to the process by which “unbearable” mental contents (e.g., those related to internal conflicts) are kept out of consciousness.
H. Kessler+5 more
semanticscholar +1 more source
‘What is ‘Czech’ in Art in Bohemia? Alfred Woltmann and defensive mechanisms of Czech artistic historiography’ [PDF]
The art historian Alfred Woltmann (1841-1880) in a lecture delivered 1876 put forth a highly provocative thesis on the predominance of the German element in the art of the Bohemian capital.
Jindrich Vybiral
doaj
Broyer du noir. Manifestations et répression policière au Québec [PDF]
Since 1999, more than 2500 political arrests have been filed in Quebec, the great majority of which took place in Montreal. This raises stakes in the domain of sociopolitical ethics, since one must determine if police officers act in a rightful way with ...
Francis Dupuis-Déri
doaj