The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Skeletal muscle PGC-1α controls whole-body lactate homeostasis through estrogen-related receptor α-dependent activation of LDH B and repression of LDH A [PDF]
, 2013 Serge Summermatter +3 more
openalex +1 more source
Currency Substitution and Financial Repression [PDF]
In this paper, we use a general equilibrium overlapping generations monetary endogenous growth model of a small open economy, to analyze whether financial repression, measured via the “high†mandatory reserve-deposit requirements of financial ...
Rangan Gupta
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10 [PDF]
, 2016 Alfa Bai +16 more
openalex +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Repressions Against the Jews in Chernivtsi Region in 1948–1953
Науковий вісник Чернівецького національного університету імені Юрія Федьковича. Історія, 2020 The article analyzes the causes, nature and methods of repressions against the Jewish population of Chernivtsi region in the last years of I. V. Stalin’s ruling. The cases of well-known Jewish poets Naphtali-Hertz Kon (Ya. I. Serf) and M. Kh.
Олександр Безаров
doaj
The Impact of British Colonialism on Irish Catholicism and National Identity: Repression, Reemergence, and Divergence [PDF]
, 2010 Timothy J. White
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Trauma and self in the Soviet context: remarks on Gulag writings [PDF]
, 2012 The present paper is a first reflection on the ideal approaches to study the corpus of lagernaia memuaristika. The author proposes the novel concept of ‘Soviet repression literature’ as a new key concept to study the whole corpus of literature related to
Gullotta, Andrea
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source