Manipulating the Light Systemic Signal HY5 Greatly Improve Fruit Quality in Tomato
This study establishes that HY5, activated by low‐dose light, acts as a systemic signal to enhance tomato fruit quality by directly promoting carotenoid synthesis and sugar metabolism. These findings demonstrate HY5's mobility from leaves to fruits and its application potential through nighttime LED lighting, offering a practical strategy for crop ...
Jiachun Wang+7 more
wiley +1 more source
Pro-democracy platform advocacy: Resisting Big Tech-mediated authoritarianism in Southeast Asia. [PDF]
Tran MV+4 more
europepmc +1 more source
Molecular Basis of Transient Repression of β-Galactosidase in Escherichia coli [PDF]
B Tyler, Boris Magasanik
openalex +1 more source
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin+3 more
wiley +1 more source
Establishment of CRISPR-STAR System to Realise Simultaneous Transcriptional Activation and Repression in Yarrowia lipolytica. [PDF]
Chen Y+8 more
europepmc +1 more source
The de-repression of thiamine biosynthesis by adenosine a tool for investigating this biosynthetic pathway [PDF]
PC Newell, R.G. Tucker
openalex +1 more source
miR-34a repression of SIRT1 regulates apoptosis
M. Yamakuchi, M. Ferlito, C. Lowenstein
semanticscholar +1 more source
SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway
Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang+9 more
wiley +1 more source
Xylose Metabolism and Transport in <i>Bacillus subtilis</i> and Its Application to D-Ribose Production. [PDF]
Park YC.
europepmc +1 more source
Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress
S. Bhattacharyya+4 more
semanticscholar +1 more source