Results 41 to 50 of about 20,465 (309)

The Prisoner Camp System in the Caspian Region of Kazakhstan in 1932-1940

open access: yesRUDN Journal of Russian History, 2022
In the study of the history of Soviet camps, there are still serious gaps; in particular, there are no works that reveal the history of the creation and functioning of the camp system in the Caspian region.
Galina M. Ivanova
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Great Purge of the 1930s in the Town of Leninsk-Kuznetskiy (Based on the Materials of the Newspapers "Leninskiy Shakhter" and "Sovetskaia Sibir")

open access: yesВестник Кемеровского государственного университета, 2020
The research featured the repressions of the 1930s, or the Great Purge. The article focuses on the case of the town of Leninsk-Kuznetskiy. The study was based on materials obtained from the press of that time (newspapers "Leninskiy Shakhter" and ...
V. A. Ovchinnikov
doaj   +1 more source

THE STRUGGLE OF THE SOVIET AUTHORITY AGAINST THE «REMNANTS OF UNIAT» IN THE UKRAINIAN SSR AT THE BREAK OF THE 1970s – 1980s

open access: yesCхід, 2021
The key methods of the Ukrainian SSR party authorities to counter the attempts of reviving the Ukrainian Greek Catholic Church in the western Ukrainian regions at the break of the 80s-90s of the XX century were considered.
РОМАН ПУЙДА
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

STORY OF FALSIFICATION OF THE CENTRAL COMMITTEE CASE INVESTIGATION “LABOR PEASANT PARTY” (ACCORDING TO THE LETTERS OF N. D. KONDRATIEV AND L. N. YUROVSKY)

open access: yesИзвестия высших учебных заведений. Поволжский регион: Гуманитарные науки, 2020
Background. Failures in socio-economic policy in rural areas in the early thirties forced the party leadership to look for the culprits for disrupting the pace of collectivization.
O. B. Mozokhin
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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