Results 41 to 50 of about 2,060 (263)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
From ‘the effect of repression’ toward ‘the response to repression’ [PDF]
Current Sociology, 2018 Scholars have long been interested in explaining the effect of state repression on political participation. Recent reviews of research on state repression highlighted contradictory findings about this effect, yet the core question is still debated: what accounts for the variation in the effects of repression?
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Some concers regarding the mass deportations of bessarabians to the USSR between 1940-1941
Astra Salvensis, 2019 In this article, the author presents a general radiography of communist repressions in Soviet Bessarabia between 1940-1941. The author makes some considerations on the nature of these repressions.
Gheorghe Cazacu
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Lithuanian laborers in Nazi-occupied Austria 1942–1945
Genocidas ir Rezistencija, 2020 The theme of forced and voluntary labor of Lithuanians in Nazi Germany has been nearly forgotten and not studied by Lithuanian historians in recent decades.
Arūnas Bubnys
doaj +1 more source
MYC in elongation and repression [PDF]
Nature Reviews Cancer, 2018 Transcription elongation supported by the super elongation complex, and H3K9 methylation and gene repression by G9a mediate the oncogenic function of Myc.
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Научный вестник МГТУ ГА, 2016 The article deals with the issue of repressions in the Red Army, particularly, at military educational establishments of Siberian Air Force Command as well as in Siberian aeroclubs training personnel for military aviation.
O. N. Astrahancev
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