Results 61 to 70 of about 5,282 (302)
The Political Repressions against Czech Intelligentsia during the “Great Terror” Times [PDF]
, 2009 В статті на підставі архівних документів висвітлюються деякі події історії України, що тісно пов’язані з перебігом масових політичних репресій проти чеської інтелігенції в добу «великого терору» на території Житомирщини.Based on the archival documents ...
Шевчук, Ю.
core +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Some concers regarding the mass deportations of bessarabians to the USSR between 1940-1941
Astra Salvensis, 2019 In this article, the author presents a general radiography of communist repressions in Soviet Bessarabia between 1940-1941. The author makes some considerations on the nature of these repressions.
Gheorghe Cazacu
doaj
Lithuanian laborers in Nazi-occupied Austria 1942–1945
Genocidas ir Rezistencija, 2020 The theme of forced and voluntary labor of Lithuanians in Nazi Germany has been nearly forgotten and not studied by Lithuanian historians in recent decades.
Arūnas Bubnys
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2023 This article deals with a little-explored part of the history of the Gypsies: the repressions against them by the Soviet state security organs in the 1930s and 1940s.
ANDRII ZHYVYUK
core +1 more source
MYC in elongation and repression [PDF]
Nature Reviews Cancer, 2018 Transcription elongation supported by the super elongation complex, and H3K9 methylation and gene repression by G9a mediate the oncogenic function of Myc.
openaire +3 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source