Results 61 to 70 of about 20,465 (309)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 2016 In “Animal Spirits” looks in some depth at several of Williams’s poems about dogs or cats written over the course of his career, from “Sub Terra” (1917); “Poem (As the cat)” (from the 1930s); the dogs of Paterson; and “To a Dog Injured in the Street ...
Schmidt, Peter
core +3 more sources
Научный вестник МГТУ ГА, 2016 The article deals with the issue of repressions in the Red Army, particularly, at military educational establishments of Siberian Air Force Command as well as in Siberian aeroclubs training personnel for military aviation.
O. N. Astrahancev
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Lithuanian laborers in Nazi-occupied Austria 1942–1945
Genocidas ir Rezistencija, 2020 The theme of forced and voluntary labor of Lithuanians in Nazi Germany has been nearly forgotten and not studied by Lithuanian historians in recent decades.
Arūnas Bubnys
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Censorship Towards the Subject of the Warsaw Uprising in Belles-Lettres in 1956–1958 [PDF]
, 2016 Right from the beginning, the subject of the Warsaw Uprising was often manipulated or even entirely erased from public discourse under the Stalinist regime.
Kloc, Agnieszka
core +2 more sources
Antimission in the Russian Orthodox Church in the late XIX – early XX century (1887–1918) [PDF]
Вестник Свято-Филаретовского института, 2014 The dynamic evolution of schism and sectarinism in the XVII century prompted the Russian Orthodox Church to embark upon antimission. This was due to a number of reasons including indiginous religiousity coupled with ignorance and serious issues in clergy’
Igor Vlasenko
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