Results 61 to 70 of about 2,060 (263)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Genocidas ir Rezistencija, 2011 After Lithuania was occupied by the USSR, and lost its statehood, the cultural, political, and scientific elite who did not emigrate, or who could not conform to the new system, suffered reprisals which complicated their lives within the Soviet reality.
Vilma Bukaitė
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Trends in Reprisals and the Persecution of Opponents of the Regime in Lithuania after 1954
Genocidas ir Rezistencija, 2012 The article analyses trends in the repressive policy against opponents of the regime in Lithuania between 1954 and 1990, identifies events and processes which determined changes in this policy, and describes methods applied by the KGB, by paying ...
Kristina Burinskaitė
doaj +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Archbishop Mečislovas Reinys: Personal Case No. 3145 of Prisoner Mečislovas Reinys
Genocidas ir Rezistencija, 2011 This article, for the first time for the Lithuanian academic community and all parties concerned, presents the case of Archbishop Mečislovas Reinys (3 February 1884–8 November 1953) from the archives of Vladimir Prison. The personal case No.
Aldona Vasiliauskienė
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Revolutionary tribunals of the Tambov province 1918–1922
Вестник Тамбовского университета. Серия: Гуманитарные наукиImportance. Reforming the public administration system is impossible without analyzing and taking into account the historical experience of the activities of punitive authorities.
S. A. Parakhin
doaj +1 more source
The Fate of Employees of the Lithuanian Forest Industry 1939–1953
Genocidas ir Rezistencija, 2012 The article explores the fate of employees of the Lithuanian State Forest Industry, a separate branch of the economy, between 1939 and 1953, the staffing policy in this industry and specific features and results of its implementation.
Algirdas Brukas
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source