Results 71 to 80 of about 20,465 (309)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Dictators, Repression and the Median Citizen: An “Eliminations Model” of Stalin’s Terror (Data from the NKVD Archives) [PDF]
This paper sheds light on dictatorial behavior as exemplified by the mass terror campaigns of Stalin. Dictatorships – unlike democracies where politicians choose platforms in view of voter preferences – may attempt to trim their constituency and thus ...
Konstantin Sonin +2 more
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Social Housing - Housing the Social: Art, Property and Spatial Justice [PDF]
, 2012 Social Housing - Housing the Social: Art, Property and Spatial Justice examines ongoing transformations in social housing and asks how these transformations are reflected in the aspirations and practices of artists.
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Historia provinciae: журнал региональной истории, 2019 The article examines Russian historiography related to the history of the internal affairs agencies in the period of Stalinism. Based on the analysis of publications by Soviet and modern Russian historians, it describes the main stages, problems and ...
Alexander Kuzminykh
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Mykhailo Hrushevskyi’s Father: Biographical Aspects [PDF]
, 2017 The key scholarly issue of contemporary Ukrainian research is not only a return to existing problems and figures but also a search for new figures and the filling of historical and biographical gaps.
Yurynets, Yaryna
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FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Museums in former residences: castles, palaces and manor houses [PDF]
, 2009 The article concerns former residences in Poland and their contemporary use as museums. The authors present the history of Polish residences, the development of museums in castles, palaces and manor houses, their spatial distribution and the relations ...
Krakowiak, Beata, Latosińska, Jolanta
core +1 more source